Neurofibromatosis (NF) type 1 (NF1), NF type 2 (NF2), and schwannomatosis constitute a
group of autosomal dominant tumor suppressor syndromes that predispose to benign and …

Neurofibromatosis 1 (NF1) is a multisystem disorder characterized by multiple café au lait
macules, intertriginous freckling, multiple cutaneous neurofibromas, and learning disability …

Abstract Neurofibromatosis type 1 (NF1), neurofibromatosis type 2 (NF2), and
schwannomatosis (SWN) are three clinically distinct tumor predisposition syndromes with a …

Abstract Neurofibromatosis type 1 (NF1), Noonan syndrome, and related syndromes,
grouped as RASopathies, result from dysregulation of the RAS-MAPK pathway and …

BRCA1‐and BRCA2‐associated hereditary breast and ovarian cancer syndromes are
among the best‐known and most extensively studied hereditary cancer syndromes …

Plexiform Neurofibromas (PN) are a common manifestation of the genetic disorder
neurofibromatosis type 1 (NF1). These benign nerve sheath tumors often cause significant …

At least 5% of cancer diagnoses are attributed to a causal pathogenic or likely pathogenic
germline genetic variant (hereditary cancer syndrome—HCS). These individuals are …

Malignant peripheral nerve sheath tumors (MPNSTs) are heterogeneous, highly aggressive
tumors with no widely effective treatment other than surgery. Genomic architecture of …

Objective To obtain updated estimates of the incidence and prevalence of neurofibromatosis
type 1 (NF1) and type 2 (NF2). Study design We conducted a systematic search of NF1 and …

Objective To determine the utility of quantitative metrics obtained from fMRI using diffusion-
weighted imaging (DWI)/apparent diffusion coefficient (ADC) mapping compared with …