Pain management in small ruminants and camelids: applications and strategies

JS Smith, J Schleining… - Veterinary Clinics: Food …, 2021 - vetfood.theclinics.com
Sheep, goats, and camelids experience pain following noxious stimuli that can come from a
range of conditions ranging from trauma and disease to production management …

Short term feeding of industrial hemp with a high cannabidiolic acid (CBDA) content increases lying behavior and reduces biomarkers of stress and inflammation in …

MD Kleinhenz, M Weeder, S Montgomery, M Martin… - Scientific reports, 2022 - nature.com
Industrial hemp (IH) is defined as Cannabis sativa containing< 0.3% delta-9
tetrahydrocannabinol (THC) and was legalized in the 2018 Farm Bill. The impact of …

[HTML][HTML] Effects of transdermal flunixin meglumine on experimentally induced lameness in adult dairy cattle

MD Kleinhenz, PJ Gorden, JS Smith, JA Schleining… - Journal of dairy …, 2019 - Elsevier
Lameness is a common animal health condition with significant production and welfare
implications. The transdermal formulation of flunixin meglumine is the only approved drug …

[HTML][HTML] Effects of a single transdermal administration of flunixin meglumine in early postpartum Holstein Friesian dairy cows: Part 1. Inflammatory and metabolic …

R Schmitt, L Pieper, S Borchardt, JM Swinkels… - Journal of Dairy …, 2023 - Elsevier
The objectives of this study were to assess the effects of a single transdermal administration
of flunixin meglumine (FM) in early postpartum Holstein Friesian dairy cows on serum …

Pharmacokinetic Parameters and Estimated Milk Withdrawal Intervals for Domestic Goats (Capra Aegagrus Hircus) After Administration of Single and Multiple …

JS Smith, TL Marmulak, JA Angelos, Z Lin… - Frontiers in Veterinary …, 2020 - frontiersin.org
Introduction: The study objectives were to estimate plasma flunixin (FLU) pharmacokinetic
parameters and milk depletion profiles for FLU and its metabolite (5-hydroxy flunixin; 5-OH) …

A novel transdermal ketoprofen formulation for analgesia in cattle

PC Mills, JG Owens, JB Reinbold… - Journal of Veterinary …, 2022 - Wiley Online Library
Ketoprofen is registered in many countries for injectable administration in cattle. Because it
is soluble in a wide range of excipients, development of a novel transdermal (TD) ketoprofen …

Residue depletion profiles and withdrawal intervals of florfenicol and its metabolite florfenicol amine in plasma and milk of lactating goats after repeated subcutaneous …

Q Chen, Z Lin, JL Davis, E Toney, MO Clapham… - Regulatory Toxicology …, 2024 - Elsevier
Florfenicol is a broad-spectrum and bacteriostatic antibiotic with a time-dependent killing
action. It is commonly used to treat respiratory diseases in goats in an extra-label manner …

A study to assess the correlation between plasma, oral fluid and urine concentrations of flunixin meglumine with the tissue residue depletion profile in finishing-age …

JL Bates, LA Karriker, SM Rajewski, Z Lin… - BMC veterinary …, 2020 - Springer
Background Flunixin meglumine (FM) was investigated for the effectiveness of plasma, oral
fluid, and urine concentrations to predict tissue residue depletion profiles in finishing-age …

Pharmacokinetics of Transdermal Flunixin Meglumine Following a Single Dose in Marine Toads (Rhinella marina)

G Scott, MM Louis, JA Balko, CM Bublitz… - Veterinary Medicine …, 2020 - Wiley Online Library
Transdermal administration is an important method of pharmacologic drug therapy in
amphibians, made possible by their unique skin physiology and permeability. Despite this …

[HTML][HTML] Determination of the milk pharmacokinetics and depletion of milk residues of flunixin following transdermal administration to lactating Holstein cows

PJ Gorden, MD Kleinhenz, R Warner, PK Sidhu… - Journal of dairy …, 2019 - Elsevier
Flunixin is a nonsteroidal anti-inflammatory drug and the most commonly prescribed
analgesic in cattle in the United States. Recently, the US Food and Drug Administration …