Sexual dimorphism in colon cancer

M Abancens, V Bustos, H Harvey, J McBryan… - Frontiers in …, 2020 - frontiersin.org
A higher incidence of colorectal cancer (CRC) is found in males compared to females.
Young women (18–44 years) with CRC have a better survival outcome compared to men of …

The prognostic utility of pre‐treatment neutrophil‐to‐lymphocyte‐ratio (NLR) in colorectal cancer: A systematic review and meta‐analysis

M Naszai, A Kurjan, TS Maughan - Cancer Medicine, 2021 - Wiley Online Library
Background Inflammation is a hallmark of cancer, and systemic markers of inflammation are
increasingly recognised as negative prognostic factors for clinical outcome. Neutrophil‐to …

Influence of sex differences on microRNA gene regulation in disease

S Sharma, M Eghbali - Biology of sex differences, 2014 - Springer
Sexual dimorphism is observed in most human diseases. The difference in the physiology
and genetics between sexes can contribute tremendously to the disease prevalence …

Perioperative COX2 and β‐adrenergic blockade improves biomarkers of tumor metastasis, immunity, and inflammation in colorectal cancer: A randomized controlled …

R Haldar, I Ricon‐Becker, A Radin, M Gutman… - Cancer, 2020 - Wiley Online Library
Background Preclinical studies have implicated excess release of catecholamines and
prostaglandins in the mediation of prometastatic processes during surgical treatment of …

Gender comparison of clinical, histopathological, therapeutic and outcome factors in 185,967 colon cancer patients

R Schmuck, M Gerken, EM Teegen, I Krebs… - … archives of surgery, 2020 - Springer
Introduction Colorectal carcinomas represent the third most common cause of cancer-
related deaths in Germany. Although the incidence is significantly higher in men compared …

Actual survival after resection of primary colorectal cancer: results from a prospective multicenter study

I van den Berg, RRJ Coebergh van den Braak… - World journal of surgical …, 2021 - Springer
Background Colorectal cancer is the third most common type of cancer in the world. We
characterize a cohort of patients who survived up to 5 years without recurrence and identify …

Cancer survival in adults in Spain: a population-based study of the spanish network of cancer registries (REDECAN)

M Guevara, A Molinuevo, D Salmerón… - Cancers, 2022 - mdpi.com
Simple Summary We studied cancer survival and its trends in adult patients in Spain. We
included more than 600,000 patients with primary cancer diagnosed during 2002–2013 and …

Racial and ethnic disparities in early-onset colorectal cancer survival

TA Zaki, PS Liang, FP May, CC Murphy - Clinical Gastroenterology and …, 2023 - Elsevier
Background Young adults diagnosed with colorectal cancer (CRC) comprise a growing, yet
understudied, patient population. We estimated 5-year relative survival of early-onset CRC …

Gene regulatory network analysis identifies sex-linked differences in colon cancer drug metabolism

CM Lopes-Ramos, ML Kuijjer, S Ogino, CS Fuchs… - Cancer research, 2018 - AACR
Understanding sex differences in colon cancer is essential to advance disease prevention,
diagnosis, and treatment. Males have a higher risk of developing colon cancer and a lower …

Survival outcomes and clinicopathological features in inflammatory bowel disease-associated colorectal cancer: a systematic review and meta-analysis

C Lu, J Schardey, T Zhang, A Crispin, U Wirth… - Annals of …, 2022 - journals.lww.com
Objective: The aim of our study was to conduct a systematic review and meta-analysis
comparing the survival outcomes of IBD-associated and non-IBD-associated CRC …