Protein folding is a biophysical process by which proteins reach a specific three-dimensional
structure. The amino acid sequence of a polypeptide chain contains all the information …

Host cell metabolism is essential for the viral replication cycle and, therefore, for productive
infection. Energy (ATP) is required for the receptor-mediated attachment of viral particles to …

Protein post-translational modification (PTM) is an important regulatory mechanism that
plays a key role in both normal and disease states. Acetylation on lysine residues is one of …

Protein acetylation is a highly frequent protein modification. However, comparatively little is
known about its enzymatic machinery. N‐α‐acetylation (NTA) and ε‐lysine acetylation (KA) …

The AMP-forming acetyl-CoA synthetase is regulated by lysine acetylation both in bacteria
and eukaryotes. However, the underlying mechanism is poorly understood. The Bacillus …

Acetyl-coenzyme A (acetyl-CoA) plays an important role in metabolism, gene expression,
signaling, and other cellular processes via transfer of its acetyl group to proteins and …

Mitochondrial fission is a crucial process in maintaining metabolic homeostasis in normal
physiology and under conditions of stress. Its dysregulation has been associated with …

Lysine acetylation (Kac), an abundant post-translational modification (PTM) in prokaryotes,
regulates various microbial metabolic pathways. However, no studies have examined …

Lysine acetylation, a ubiquitous and dynamic regulatory posttranslational modification
(PTM), affects hundreds of proteins across all domains of life. In bacteria, lysine acetylation …

Inducing protein degradation by proteolysis targeting chimera (PROTAC) has provided great
opportunities for scientific research and industrial applications. Histone deacetylase (HDAC) …