[HTML][HTML] Extracellular vesicles, from the pathogenesis to the therapy of neurodegenerative diseases

X Xia, Y Wang, JC Zheng - Translational Neurodegeneration, 2022 - Springer
Extracellular vesicles (EVs) are small bilipid layer-enclosed vesicles that can be secreted by
all tested types of brain cells. Being a key intercellular communicator, EVs have emerged as …

[HTML][HTML] Therapeutic utility of mesenchymal stromal cell (MSC)-based approaches in chronic neurodegeneration: a glimpse into underlying mechanisms, current status …

M Rahbaran, AO Zekiy, M Bahramali… - Cellular & Molecular …, 2022 - Springer
Recently, mesenchymal stromal cell (MSC)-based therapy has become an appreciated
therapeutic approach in the context of neurodegenerative disease therapy. Accordingly, a …

[HTML][HTML] Mesenchymal stem cell mechanisms of action and clinical effects in osteoarthritis: a narrative review

V Molnar, E Pavelić, K Vrdoljak, M Čemerin, E Klarić… - Genes, 2022 - mdpi.com
With the insufficient satisfaction rates and high cost of operative treatment for osteoarthritis
(OA), alternatives have been sought. Furthermore, the inability of current medications to …

[HTML][HTML] Therapeutic potential of exosomes derived from adipose tissue-sourced mesenchymal stem cells in the treatment of neural and retinal diseases

CR Harrell, V Volarevic, V Djonov… - International journal of …, 2022 - mdpi.com
Therapeutic agents that are able to prevent or attenuate inflammation and ischemia-induced
injury of neural and retinal cells could be used for the treatment of neural and retinal …

[HTML][HTML] Exosomes derived from human amniotic fluid mesenchymal stem cells preserve microglia and neuron cells from Aβ

M Zavatti, M Gatti, F Beretti, C Palumbo… - International Journal of …, 2022 - mdpi.com
Background: Neuroinflammation is involved in neuronal cell death that occurs in
neurodegenerative diseases such as Alzheimer's disease (AD). Microglia play important …

Therapeutic efficacy and promise of stem cell-derived extracellular vesicles in Alzheimer's disease and other aging-related disorders

HA Rather, S Almousa, S Craft, G Deep - Ageing Research Reviews, 2023 - Elsevier
The term extracellular vesicles (EVs) refers to a variety of heterogeneous nanovesicles
secreted by almost all cell types, primarily for intercellular communication and maintaining …

[HTML][HTML] News about therapies of alzheimer's disease: Extracellular vesicles from stem cells exhibit advantages compared to other treatments

J Meldolesi - Biomedicines, 2022 - mdpi.com
Upon its discovery, Alzheimer's, the neurodegenerative disease that affects many millions of
patients in the world, remained without an effective therapy. The first drugs, made available …

Biogenic silver NPs alleviate LPS-induced neuroinflammation in a human fetal brain-derived cell line: Molecular switch to the M2 phenotype, modulation of TLR4 …

A Sharma, V Jaiswal, M Park, HJ Lee - Biomaterials advances, 2023 - Elsevier
Silver nanoparticles (AgNPs) have inconsistent findings against inflammation. Although a
wealth of literature on the beneficial effects of green-synthesized AgNPs has been …

α-Gal Nanoparticles in CNS Trauma: I. In Vitro Activation of Microglia Towards a Pro-Healing State

B Gopalakrishnan, U Galili, A Dunbar, L Solorio… - Tissue Engineering and …, 2024 - Springer
Background: Macrophages and microglia play critical roles after spinal cord injury (SCI), with
the pro-healing, anti-inflammatory (M2) subtype being implicated in tissue repair. We …

Honeyberry-derived carbon quantum dots ameliorate LPS-induced neuroinflammation and oxidative stress through Nrf2/HO-1 signalling in HMC3 cells

Sanjay, A Sharma, HJ Lee - Artificial Cells, Nanomedicine, and …, 2023 - Taylor & Francis
Carbon quantum dots (CQDs) were synthesized from blue honeysuckle (Lonicera caerulea)
berry fruit extracts using a well-known, cost-effective, and environmental friendly …