Novel diagnostic biomarkers in colorectal cancer

AL Zygulska, P Pierzchalski - International journal of molecular sciences, 2022 - mdpi.com
Colorectal cancer (CRC) is still a leading cause of cancer death worldwide. Less than half of
cases are diagnosed when the cancer is locally advanced. CRC is a heterogenous disease …

Network approach in liquidomics landscape

D Santini, A Botticelli, A Galvano, M Iuliani… - Journal of Experimental …, 2023 - Springer
Tissue-based biopsy is the present main tool to explore the molecular landscape of cancer,
but it also has many limits to be frequently executed, being too invasive with the risk of side …

Dysbiosis of human gut microbiome in young-onset colorectal cancer

Y Yang, L Du, D Shi, C Kong, J Liu, G Liu, X Li… - Nature …, 2021 - nature.com
The incidence of sporadic young-onset colorectal cancer (yCRC) is increasing. A significant
knowledge gap exists in the gut microbiota and its diagnostic value for yCRC patients …

Identification of faecal extracellular vesicles as novel biomarkers for the non‐invasive diagnosis and prognosis of colorectal cancer

Z Zhang, X Liu, X Yang, Y Jiang, A Li… - Journal of …, 2023 - Wiley Online Library
Colorectal cancer (CRC) is one of the most common malignancies that is usually detected
late in the clinic. The currently available diagnostic tools for CRC are either invasive or …

The interaction of Akkermansia muciniphila with host-derived substances, bacteria and diets

T Hagi, C Belzer - Applied microbiology and biotechnology, 2021 - Springer
Trillions of microbes inhabit the human gut and build extremely complex communities. Gut
microbes contribute to host metabolisms for better or worse and are widely studied and …

[HTML][HTML] A fecal microRNA signature by small RNA sequencing accurately distinguishes colorectal cancers: results from a multicenter study

B Pardini, G Ferrero, S Tarallo, G Gallo, A Francavilla… - Gastroenterology, 2023 - Elsevier
Background & Aims Fecal tests currently used for colorectal cancer (CRC) screening show
limited accuracy in detecting early tumors or precancerous lesions. In this respect, we …

Current advances in detecting genetic and epigenetic biomarkers of colorectal cancer

MS Islam, V Gopalan, AKY Lam… - Biosensors and …, 2023 - Elsevier
Colorectal carcinoma (CRC) is the third most common cancer in terms of diagnosis and the
second in terms of mortality. Recent studies have shown that various proteins, such as …

Epigenetic landscape of liquid biopsy in colorectal cancer

A Rodriguez-Casanova, N Costa-Fraga… - Frontiers in Cell and …, 2021 - frontiersin.org
Colorectal cancer (CRC) is one of the most common malignancies and is a major cause of
cancer-related deaths worldwide. Thus, there is a clinical need to improve early detection of …

A novel urinary miRNA biomarker for early detection of colorectal cancer

H Iwasaki, T Shimura, M Kitagawa, T Yamada… - Cancers, 2022 - mdpi.com
Simple Summary Early diagnosis is critically important to achieve life-saving therapy for
colorectal cancer (CRC). Since colonoscopy is not suitable as a screening method for CRC …

Fecal microRNAs as innovative biomarkers of intestinal diseases and effective players in host-microbiome interactions

M Sarshar, D Scribano, C Ambrosi, AT Palamara… - Cancers, 2020 - mdpi.com
Over the past decade, short non-coding microRNAs (miRNAs), including circulating and
fecal miRNAs have emerged as important modulators of various cellular processes by …