[HTML][HTML] Melatonin maximizes the therapeutic potential of non-preconditioned MSCs in a DEN-induced rat model of HCC

MA El-Magd, Y Mohamed, ES El-Shetry… - Biomedicine & …, 2019 - Elsevier
Pretreatment of mesenchymal stem cells (MSCs) with melatonin (Mel) improves their
potential therapeutic effect on chronic diseases and cancers. However, this preconditioning …

[HTML][HTML] The potential therapeutic effect for melatonin and mesenchymal stem cells on hepatocellular carcinoma

Y Mohamed, MA Basyony, NI El-Desouki, WS Abdo… - BioMedicine, 2019 - ncbi.nlm.nih.gov
Background/aim: Herein, we investigated the potential therapeutic effect of Melatonin (Mel)
and/or mesenchymal stem cells (MSCs) on rat model of HCC. Materials and Methods …

Hepatoprotective effect of Origanum vulgare in Wistar rats against carbon tetrachloride-induced hepatotoxicity

M Sikander, S Malik, K Parveen, M Ahmad, D Yadav… - Protoplasma, 2013 - Springer
The effect of an aqueous extract of Origanum vulgare (OV) leaves extract on CCl 4-induced
hepatotoxicity was investigated in normal and hepatotoxic rats. To evaluate the …

Effect of diosmin on apoptotic signaling molecules in N-nitrosodiethylamine-induced hepatocellular carcinoma in experimental rats

S Perumal, K Langeshwaran, J Selvaraj… - Molecular and cellular …, 2018 - Springer
The aim of the present study was to evaluate the antioxidant and chemopreventive efficiency
of diosmin against N-nitrosodiethylamine (NDEA)-induced hepatocarcinogenesis in adult …

Elevated expression of cellular SYNE1, MMP10, and GTPase1 and their regulatory role in hepatocellular carcinoma progression

LH Faraj Shaglouf, M Ranjpour, S Wajid, SK Jain - Protoplasma, 2020 - Springer
Hepatocellular carcinoma (HCC) is the most common primary liver malignancy resulting in
high mortality. HCC progression is associated with abnormal signal transduction that …

The in vivo antineoplastic and therapeutic efficacy of troxerutin on rat preneoplastic liver: biochemical, histological and cellular aspects

NS Thomas, K George, S Arivalagan, V Mani… - European journal of …, 2017 - Springer
Purpose Troxerutin (TXER), a trihydroxyethylated derivative of the natural bioflavonoid rutin,
abundantly found in tea, various fruits and vegetables, is known to exhibit ample …

Elevated expression of ISY1, APOA-1, SYNE1, MTG1, and MMP10 at HCC initiation: HCC specific protein network involving interactions of key regulators of lipid …

LHF Shaglouf, M Ranjpour, S Wajid, R Tandon… - Protoplasma, 2023 - Springer
Identification of molecular regulators of hepatocellular carcinoma (HCC) initiation and
progression is not well understood. We chemically induced HCC in male Wistar rats by …

[HTML][HTML] Oxidative stress and cell damage in a model of precancerous lesions and advanced hepatocellular carcinoma in rats

AJ Moreira, G Rodrigues, S Bona, CT Cerski… - Toxicology reports, 2015 - Elsevier
Hepatocellular carcinoma (HCC) is the third most frequent cause of cancer deaths
throughout the world. This study was aimed to analyze oxidative stress and cell damage in a …

[PDF][PDF] Hepatoprotective effect of royal jelly, grape seed extract, and Lycium barbarum against diethylnitrosamine-induced liver toxicity in rats

S Bilgic, Z Dogan, S Azirak, ME Erdemli, M Onderci… - 2018 - annalsmedres.org
Aim: We aimed to investigate, the effects of royal jelly (RJ), grape seed extract (GSE), and
Lycium barbarum extract (LBAE) against diethylnitrosamine (DEN) induced hepatotoxicity, in …

Elevated expression of A-Raf and FA2H in hepatocellular carcinoma is associated with lipid metabolism dysregulation and cancer progression

M Ranjpour, S Wajid, SK Jain - Anti-Cancer Agents in Medicinal …, 2019 - ingentaconnect.com
Background: Identification of events leading to hepatocellular carcinoma (HCC) progression
is essential for understanding its pathophysiology. The aims of this study are to identify and …