Although heart valve replacement is among the most common cardiovascular surgical
procedures, their outcome is often difficult to predict. One of the reasons is the design and …

In the past two decades, major advances have been made in the clinical evaluation and
treatment of valvular heart disease owing to the advent of noninvasive cardiac imaging …

Treatment of mitral valve (MV) diseases requires comprehensive clinical evaluation and
therapy personalization to optimize outcomes. Finite-element models (FEMs) of MV …

We aim at testing the possibility to build patient-specific structural finite element models
(FEMs) of the mitral valve (MV) from cardiac magnetic resonance (CMR) imaging and to use …

This study aimed to characterize the mechanical properties of aged human anterior mitral
leaflets (AML) and posterior mitral leaflets (PML). The AML and PML samples from …

Computational simulations are playing an increasingly important role in enhancing our
understanding of the normal human physiological function, etiology of diseased states …

Dysfunction of mitral valve causes morbidity and premature mortality and remains a leading
medical problem worldwide. Computational modelling aims to understand the biomechanics …

Valve treatment simulation is performed from patient specific imaging data for therapy
planning. A model of the valve may be generated from the patient specific data automatically …

The mitral valve is a complex apparatus with multiple constituents that work cohesively to
ensure unidirectional flow between the left atrium and ventricle. Disruption to any or all of the …

Edge-to-edge repair for mitral valve regurgitation is being increasingly performed in high-
surgical risk patients using minimally invasive mitral clipping devices. Known procedural …