Central sensitisation in chronic pain conditions: latest discoveries and their potential for precision medicine

J Nijs, SZ George, DJ Clauw… - The Lancet …, 2021 - thelancet.com
Chronic pain is a leading cause of disability globally and associated with enormous health-
care costs. The discrepancy between the extent of tissue damage and the magnitude of …

Clinical Psychology and Clinical Immunology: is there a link between Alexithymia and severe Asthma?

L Ricciardi, G Spatari, CM Vicario… - … Journal of Clinical …, 2023 - researchonline.ljmu.ac.uk
Background: Severe asthma patients are those suffering from asthma exacerbations despite
adherence to maximal optimized asthma treatment such as high dose inhalant …

[HTML][HTML] Inflammatory rheumatic diseases and the risk of Parkinson's disease: A systematic review and meta-analysis

L He, H Zhao, F Wang, X Guo - Frontiers in Neurology, 2022 - frontiersin.org
Background Several studies showed inconsistencies in the relationships between
inflammatory rheumatic diseases (IRDs) and the risk of Parkinson's disease (PD). Therefore …

[HTML][HTML] Structural and functional abnormalities in knee osteoarthritis pain revealed with multimodal magnetic resonance imaging

H Guo, Y Wang, L Qiu, X Huang, C He… - Frontiers in Human …, 2021 - frontiersin.org
The knee osteoarthritis (KOA) pain is the most common form of arthritis pain affecting
millions of people worldwide. Long-term KOA pain causes motor impairment and affects …

Elevated highly sensitive C-reactive protein in fibromyalgia associates with symptom severity

T Zetterman, R Markkula, E Kalso - Rheumatology Advances in …, 2022 - academic.oup.com
Objectives Fibromyalgia (FM), a common pain syndrome, is thought to be a non-
inflammatory, nociplastic condition, but evidence implicating neuroinflammation has been …

[HTML][HTML] Serum S100A8/A9 concentrations are associated with neuropsychiatric involvement in systemic lupus erythematosus: a cross-sectional study

KA Zervides, A Jern, J Nystedt, B Gullstrand… - BMC rheumatology, 2022 - Springer
Background Neuropsychiatric (NP) involvement and fatigue are major problems in systemic
lupus erythematosus (SLE). S100A8/A9 is a marker of inflammation and responds to therapy …

Identifying the most important confounders when assessing the association between low-grade systemic inflammation and musculoskeletal pain: A modified Delphi …

MA Koop, IJ Lutke Schipholt… - Pain …, 2021 - academic.oup.com
Objective The association between low-grade systemic inflammation and musculoskeletal
pain may be influenced by multiple factors. However, little is known about the relative …

Clinical and functional impact of central sensitization on patients with familial Mediterranean fever: a cross-sectional study

FN Yücel, HH Gezer, J Jandaulyet, N Öz… - Rheumatology …, 2023 - Springer
This study aimed to investigate the frequency of CS and its clinical and functional effects on
familial Mediterranean fever (FMF). A hundred FMF patients were included in this study. The …

Central sensitization in axial spondyloarthritis: an explorative study with quantitative sensory testing and clinical scales

FN Yücel, MT Duruöz - Modern Rheumatology, 2022 - academic.oup.com
Objectives To evaluate the central sensitization (CS) and the related parameters in patients
with axial spondyloarthritis (axSpA). Methods Quantitative sensory testing (QST) which …

Pharmacotherapy for osteoarthritis-related pain: current and emerging therapies

M Zhang, Z Wang, C Ding - Expert Opinion on Pharmacotherapy, 2024 - Taylor & Francis
Introduction Osteoarthritis (OA) related pain has affected millions of people worldwide.
However, the current pharmacological options for managing OA-related pain have not …