Obstetrical hemorrhage and especially DIC (disseminated intravascular coagulation) is a
leading cause for maternal mortality across the globe, often secondary to underlying …

In normal pregnancy, there is a marked increase in the procoagulant activity in maternal
blood characterized by elevation of factors VII, X, VIII, fibrinogen and von Willebrand factor …

Background Pregnant women are at increased risk for severe outcomes from coronavirus
disease 2019 (COVID-19), but the pathophysiology underlying this increased morbidity and …

Cell–cell communication is an essential mechanism for the maintenance and development
of various organs, including the female reproductive system. Today, it is well-known that the …

Disseminated intravascular coagulation (DIC) is a life-threatening situation that can arise
from a variety of obstetrical and nonobstetrical causes. Obstetrical DIC has been associated …

Microvesicles (MVs) which include microparticles (MPs) and exosomes are found in blood
circulation in normal physiologic conditions and are increased in a variety of diseases. This …

As activation of the coagulation pathway is a physiological response to injury, the
development of disseminated intravascular coagulation (DIC) is a warning signal to the …

Absence of the blood coagulation inhibitor thrombomodulin (Thbd) from trophoblast cells of
the mouse placenta causes a fatal arrest of placental morphogenesis. The pathogenesis of …

Intrauterine growth restriction (IUGR) is a serious pathological complication associated with
compromised fetal development during pregnancy. The aim of the study was to broaden …

Preeclampsia is a hypertensive pregnancy disorder characterized by development of
hypertension and proteinuria after 20 weeks of gestation that remains a leading cause of …