Role of mesenchymal stromal cells as therapeutic agents: potential mechanisms of action and implications in their clinical use

GJ Jimenez-Puerta, JA Marchal, E López-Ruiz… - Journal of clinical …, 2020 - mdpi.com
Due to the great therapeutic interest that involves the translation of mesenchymal stromal
cells (MSCs) into clinical practice, they have been widely studied as innovative drugs, in …

Mechanisms behind therapeutic potentials of mesenchymal stem cell mitochondria transfer/delivery

K Malekpour, A Hazrati, S Soudi… - Journal of Controlled …, 2023 - Elsevier
Mesenchymal stromal/stem cells (MSCs) perform their therapeutic effects through various
mechanisms, including their ability to differentiate, producing different growth factors …

The importance of HLA assessment in “off-the-shelf” allogeneic mesenchymal stem cells based-therapies

M Kot, M Baj-Krzyworzeka, R Szatanek… - International Journal of …, 2019 - mdpi.com
The need for more effective therapies of chronic and acute diseases has led to the attempts
of developing more adequate and less invasive treatment methods. Regenerative medicine …

Administration of adipose derived mesenchymal stem cells and platelet lysate in erectile dysfunction: a single center pilot study

V Protogerou, E Michalopoulos, P Mallis, I Gontika… - Bioengineering, 2019 - mdpi.com
Erectile dysfunction (ED) affects more than 30 million men; endothelial dysfunction plays a
significant role in EDs pathogenesis. The aim of this study was to administer mesenchymal …

[HTML][HTML] Mesenchymal stromal cells as potential immunomodulatory players in severe acute respiratory distress syndrome induced by SARS-CoV-2 infection

P Mallis, E Michalopoulos… - World Journal of Stem …, 2020 - ncbi.nlm.nih.gov
Severe acute respiratory syndrome coronavirus-2 and the related coronavirus disease-19
(COVID-19) is a worldwide emerging situation, which was initially reported in December …

Interplay between mesenchymal stromal cells and immune system: Clinical applications in immune-related diseases

P Mallis, E Michalopoulos… - Exploration of …, 2021 - explorationpub.com
Mesenchymal stromal cells (MSCs) are a mesodermal stem cell population, with known self-
renewal and multilineage differentiation properties. In the last century, MSCs have been …

The combined use of stem cells and platelet lysate plasma for the treatment of erectile dysfunction: A pilot study–6 months results

V Protogerou, SE Beshari, E Michalopoulos, P Mallis… - Medicines, 2020 - mdpi.com
Background: The current treatment of Erectile Dysfunction (ED) is mainly based on the use
of drugs that provide erections shortly after use but they do not really treat the problem. Stem …

[HTML][HTML] Mesenchymal stromal cell delivery as a potential therapeutic strategy against COVID-19: Promising evidence from in vitro results

P Mallis, T Chatzistamatiou, Z Dimou… - World Journal of …, 2022 - ncbi.nlm.nih.gov
BACKGROUND Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is
responsible for the coronavirus disease 2019 (COVID-19) pandemic, which was initiated in …

The combinatory effect of scaffold topography and culture condition: An approach to nucleus pulposus tissue engineering

N Vanawati, A Barlian, H Judawisastra… - Future Science …, 2022 - Taylor & Francis
Scaffold topography and culture medium conditions for human wharton's jelly mesenchymal
stem cells (hWJ-MSC) are critical components of the approach to nucleus pulposus (NP) …

Efficient Decellularization of the Full-Thickness Rat-Derived Abdominal Wall to Produce Acellular Biologic Scaffolds for Tissue Reconstruction: Promising Evidence …

G Skepastianos, P Mallis, E Kostopoulos… - Bioengineering, 2023 - mdpi.com
Background: Functional restoration of abdominal wall defects represents one of the
fundamental challenges of reconstructive surgery. Synthetic grafts or crosslinked animal …