Purpose To review the basic science studies on platelet-rich plasma (PRP) for cartilage and
determine whether there has been an improvement in methodology and outcome reporting …

Nowadays, research in Tissue Engineering and Regenerative Medicine is focusing on the
identification of instructive scaffolds to address the requirements of both clinicians and …

Articular cartilage damage and wear can result in cartilage degeneration, ultimately
culminating in osteoarthritis. Current surgical interventions offer limited capacity for cartilage …

Purpose The aim of the present study is to investigate and compare the effects of biological
adjuvants (platelet-rich plasma, platelet-rich fibrin matrix) and microfracture technique …

Animal assays represent an important stage between in vitro studies and human clinical
applications. These models are crucial for biomedical research and regenerative medicine …

The current study aimed to evaluate the effects of chemokine stromal cell-derived factor
(SDF)-1α and platelet-rich plasma (PRP) on bone formation and angiogenesis, and to …

Articular cartilage is avascular and aneural, and has limited capacity for self‑regeneration
when injured. Tissue engineering has emerged as a promising approach in repairing …

CXC motif chemokine ligand 12 (CXCL12), often referred to as stromal cell–derived factor 1
(SDF-1), is a crucial factor for musculoskeletal biology. SDF-1 is a powerful chemokine that …

Despite progress, osteochondral (OC) tissue engineering strategies face limitations in terms
of articular cartilage layer development and its integration with the underlying bone tissue …

Platelet concentrates (PCs), including platelet-rich plasma (PRP) gel and platelet-rich fibrin
(PRF), are autologous blood-derived biomaterials containing numerous growth factors. This …