Alopecia areata: a review of the role of oxidative stress, possible biomarkers, and potential novel therapeutic approaches

L Peterle, S Sanfilippo, F Borgia, N Cicero, S Gangemi - Antioxidants, 2023 - mdpi.com
Alopecia areata (AA) is a dermatological condition characterized by non-scarring hair loss.
Exact etiopathogenesis of AA is still unknown although it is known that several factors …

Gut microbiome, metabolome and alopecia areata

Z Liu, X Liu - Frontiers in Microbiology, 2023 - frontiersin.org
Alopecia areata (AA) is a type of dermatological disease characterized by rapid and non-
scarring hair loss of the scalp or body skin that may be related to genetic, immunological and …

Novel potential therapeutic targets of alopecia areata

W Xu, S Wan, B Xie, X Song - Frontiers in Immunology, 2023 - frontiersin.org
Alopecia areata (AA) is a non-scarring hair loss disorder caused by autoimmunity. The
immune collapse of the hair follicle, where interferon-gamma (IFN-γ) and CD8+ T cells …

Hair repigmentation and regrowth in a dupilumab-treated paediatric patient with alopecia areata and atopic dermatitis: a case report

X Yan, M Tayier, ST Cheang, Z Liao… - … in Chronic Disease, 2023 - journals.sagepub.com
Alopecia areata (AA) is a chronic inflammatory disease mainly involving Th1
immunoreaction, but Th2 is also involved. A 9-year-old girl presented to our clinic with …

The potential of regulatory T cell-based therapies for alopecia areata

S Wan, W Xu, B Xie, C Guan, X Song - Frontiers in Immunology, 2023 - frontiersin.org
Cytotoxic T lymphocyte has been a concern for the etiopathogenesis of alopecia areata
(AA), some recent evidence suggests that the regulatory T (Treg) cell deficiency is also a …

Topical drug delivery strategies for enhancing drug effectiveness by skin barriers, drug delivery systems and individualized dosing

L Zhao, J Chen, B Bai, G Song, J Zhang, H Yu… - Frontiers in …, 2024 - frontiersin.org
Topical drug delivery is widely used in various diseases because of the advantages of not
passing through the gastrointestinal tract, avoiding gastrointestinal irritation and hepatic first …

The multifaceted role of autophagy in skin autoimmune disorders: a guardian or culprit?

Y Lin, X Wu, Y Yang, Y Wu, L Xiang… - Frontiers in …, 2024 - frontiersin.org
Autophagy is a cellular process that functions to maintain intracellular homeostasis via the
degradation and recycling of defective organelles or damaged proteins. This dynamic …

Association between genetically predicted leukocyte telomere length and non-scarring alopecia: a two-sample Mendelian randomization study

Y Li, S Yang, M Liao, Z Zheng, M Li, X Wei… - Frontiers in …, 2023 - frontiersin.org
Background The most commonly acknowledged non-scarring alopecia are androgenetic
alopecia (AGA) and alopecia areata (AA). Previous studies have revealed various risk …

The clinical and immunological features of alopecia areata following SARS-CoV-2 infection or COVID-19 vaccines

S Fu, X Song - Expert Opinion on Therapeutic Targets, 2024 - Taylor & Francis
Introduction Alopecia areata (AA) is an autoimmune disease induced by viral infection or
vaccination. With the increased incidence of severe acute respiratory syndrome coronavirus …

Pathogenesis of Alopecia Areata and Vitiligo: Commonalities and Differences

HL Yamaguchi, Y Yamaguchi, E Peeva - International Journal of …, 2024 - mdpi.com
Both alopecia areata (AA) and vitiligo are distinct, heterogenous, and complex disease
entities, characterized by nonscarring scalp terminal hair loss and skin pigment loss …