Therapeutic targets in lung tissue remodelling and fibrosis

G Liu, AM Philp, T Corte, MA Travis, H Schilter… - Pharmacology & …, 2021 - Elsevier
Structural changes involving tissue remodelling and fibrosis are major features of many
pulmonary diseases, including asthma, chronic obstructive pulmonary disease (COPD) and …

Pathology of asthma

M Kudo, Y Ishigatsubo, I Aoki - Frontiers in microbiology, 2013 - frontiersin.org
Asthma is a serious health and socioeconomic issue all over the world, affecting more than
300 million individuals. The disease is considered as an inflammatory disease in the airway …

[图书][B] The mathematics and mechanics of biological growth

A Goriely - 2017 - books.google.com
This monograph presents a general mathematical theory for biological growth. It provides
both a conceptual and a technical foundation for the understanding and analysis of …

The nature of small-airway obstruction in chronic obstructive pulmonary disease

JC Hogg, F Chu, S Utokaparch, R Woods… - … England Journal of …, 2004 - Mass Medical Soc
Background Chronic obstructive pulmonary disease (COPD) is a major public health
problem associated with long-term exposure to toxic gases and particles. We examined the …

Asthma: from bronchoconstriction to airways inflammation and remodeling

J Bousquet, PK Jeffery, WW Busse… - American journal of …, 2000 - atsjournals.org
Asthma | From Bronchoconstriction to Airways Inflammation and Remodeling | American
Journal of Respiratory and Critical Care Medicine ATS Journals Logo Official Publications …

The pathology of chronic obstructive pulmonary disease

JC Hogg, W Timens - Annual Review of Pathology: Mechanisms …, 2009 - annualreviews.org
The pathogenesis of chronic obstructive pulmonary disease (COPD) is based on the innate
and adaptive inflammatory immune response to the inhalation of toxic particles and gases …

The role of substance P in inflammatory disease

TM O'Connor, J O'Connell, DI O'Brien… - Journal of cellular …, 2004 - Wiley Online Library
The diffuse neuroendocrine system consists of specialised endocrine cells and peptidergic
nerves and is present in all organs of the body. Substance P (SP) is secreted by nerves and …

[HTML][HTML] Chronic inflammation and asthma

JR Murdoch, CM Lloyd - Mutation Research/Fundamental and Molecular …, 2010 - Elsevier
Allergic asthma is a complex and chronic inflammatory disorder which is associated with
airway hyper-responsiveness and tissue remodelling of the airway structure. Although …

Airway remodeling heterogeneity in asthma and its relationship to disease outcomes

A Hsieh, N Assadinia, TL Hackett - Frontiers in physiology, 2023 - frontiersin.org
Asthma affects an estimated 262 million people worldwide and caused over 461,000 deaths
in 2019. The disease is characterized by chronic airway inflammation, reversible …

CD8+ T-Lymphocytes in Peripheral Airways of Smokers with Chronic Obstructive Pulmonary Disease

M Saetta, A Di STEFANO, G Turato… - American journal of …, 1998 - atsjournals.org
To investigate whether the inflammatory process in peripheral airways is different in smokers
who develop symptoms of chronic bronchitis and chronic airflow limitation and in …