Alzheimer's disease (AD) is a neurodegenerative disorder that impairs mental ability
development and interrupts neurocognitive function. This neuropathological condition is …

Medicinal plants have been used for years as a source of food, spices, and, in traditional
medicine, as a remedy to numerous diseases. Piper nigrum, belonging to the family …

Piper species are aromatic plants used as spices in the kitchen, but their secondary
metabolites have also shown biological effects on human health. These plants are rich in …

The nervous system is a crucial component of the body and damages to this system, either
by of injury or disease, can result in serious or potentially lethal consequences. Restoring …

Abstract According to the Alzheimer Association Report (2017), Alzheimer's disease (AD) is
the 6th primary cause of death in the USA, which affects nearly 5.5 million people. In the …

Piperine is the major bio‐active component of pepper, which imparts pungency and biting
taste to it. This naturally occurring alkaloid has numerous demonstrated health effects and …

CNS disorders are on the rise despite advancements in our understanding of their
pathophysiological mechanisms. A major hurdle to the treatment of these disorders is the …

Since the application of chitosan magnetic cationic microspheres in brain drug delivery by
Gallo in 1993, chitosan has been extensively studied in brain drug delivery. As the only …

Most of the available drugs are usually administered orally (eg in tablets or capsules) or by
parenteral injection in the case of substances being destroyed in the gastric environment or …

Extensive research within the last several decades has revealed that the major risk factors
for most chronic diseases are infections, obesity, alcohol, tobacco, radiation, environmental …