An updated overview of metabolomic profile changes in chronic obstructive pulmonary disease

N Ran, Z Pang, Y Gu, H Pan, X Zuo, X Guan, Y Yuan… - Metabolites, 2019 - mdpi.com
Chronic obstructive pulmonary disease (COPD), a common and heterogeneous respiratory
disease, is characterized by persistent and incompletely reversible airflow limitation …

Identification of lipid biomarker from serum in patients with chronic obstructive pulmonary disease

D Liu, M Meister, S Zhang, CI Vong, S Wang… - Respiratory …, 2020 - Springer
Background Chronic obstructive pulmonary disease (COPD) is the third leading cause of
death in the United States with no effective treatment. The current diagnostic method …

Plasma metabolomics and lipidomics reveal perturbed metabolites in different disease stages of chronic obstructive pulmonary disease

J Zhou, Q Li, C Liu, R Pang, Y Yin - International Journal of …, 2020 - Taylor & Francis
Background Chronic obstructive pulmonary disease (COPD) is a common disease
characterized by persistent respiratory symptoms and airflow restriction. It is usually …

Integrated metabolomics, network pharmacology and biological verification to reveal the mechanisms of Nauclea officinalis treatment of LPS-induced acute lung …

H Xu, S Xu, L Li, Y Wu, S Mai, Y Xie, Y Tan, A Li… - Chinese Medicine, 2022 - Springer
Background Acute lung injury (ALI) is a severe inflammatory disease, underscoring the
urgent need for novel treatments. Nauclea officinalis Pierre ex Pitard (Danmu in Chinese …

Metabolomic profile perturbations of serum, lung, bronchoalveolar lavage fluid, spleen and feces in LPS-induced acute lung injury rats based on HPLC-ESI-QTOF-MS

T Wang, S Lin, R Liu, H Li, Z Liu, X Zhang, H Xu… - Analytical and …, 2020 - Springer
Acute lung injury (ALI) is a clinically common and serious disease, underscoring the urgent
need for clarification of its pathogenesis. According to traditional Chinese medicine (TCM) …

Ginger extract extends the lifespan of Drosophila melanogaster through antioxidation and ameliorating metabolic dysfunction

Y Zhou, L Xue, L Gao, X Qin, G Du - Journal of Functional Foods, 2018 - Elsevier
Ginger, a kind of foods supplement, is rich in gingerols, shogaols and paradols, possesses
extensive pharmacological activities. The aim of this study was to investigate the anti-aging …

Study on the mechanism of anti-hepatic fibrosis of Glycyrrhiza Uralensis-Salvia miltiorrhiza prescription based on serum and urine metabolomics and network …

B Hong, Y Wang, Y Hou, R Liu, W Li - Journal of Chromatography B, 2022 - Elsevier
Hepatic fibrosis (HF) is a kind of chronic epidemic liver disease. Glycyrrhiza Uralensis and
Salvia Miltiorrhiza (GUSM), traditional Chinese medicine, has the obvious clinical treatment …

Metabolomics coupled with network pharmacology study on the protective effect of Keguan-1 granules in LPS-induced acute lung injury

S Chen, M Zhou, X Zhao, Y Han, Y Huang… - Pharmaceutical …, 2022 - Taylor & Francis
Abstract Context Keguan-1 (KG-1) plays a vital role in enhancing the curative effects,
improving quality of life, and reducing the development of acute lung injury (ALI). Objective …

Role of Liver Growth Factor (LGF) in Parkinson's Disease: Molecular Insights and Therapeutic Opportunities

E Angelopoulou, YN Paudel, C Piperi - Molecular Neurobiology, 2021 - Springer
Parkinson's disease is the most common neurodegenerative movement disorder with
unclear etiology and only symptomatic treatment to date. Toward the development of novel …

Serum metabolomics using ultra‐high performance liquid chromatography–Q‐Exactive tandem mass spectrometry reveals the mechanism of action of exercise …

Y Du, J Wu, Y Tian, L Zhang, P Zhao… - Biomedical …, 2023 - Wiley Online Library
Exercise training is the cornerstone component of pulmonary rehabilitation, which results in
symptom‐reducing, psychosocial, and health economic benefits for chronic obstructive …