miRNAs as biomarkers in disease: latest findings regarding their role in diagnosis and prognosis

CE Condrat, DC Thompson, MG Barbu, OL Bugnar… - Cells, 2020 - mdpi.com
MicroRNAs (miRNAs) represent a class of small, non-coding RNAs with the main roles of
regulating mRNA through its degradation and adjusting protein levels. In recent years …

MicroRNA

TX Lu, ME Rothenberg - Journal of allergy and clinical immunology, 2018 - Elsevier
MicroRNAs (miRNAs) are small endogenous RNAs that regulate gene-expression
posttranscriptionally. MiRNA research in allergy is expanding because miRNAs are crucial …

MicroRNA as biomarkers and diagnostics

J Wang, J Chen, S Sen - Journal of cellular physiology, 2016 - Wiley Online Library
MicroRNAs (miRNAs) are a group of small non‐coding RNAs that are involved in regulating
a range of developmental and physiological processes; their dysregulation has been …

Rationally engineered nucleic acid architectures for biosensing applications

M Xiao, W Lai, T Man, B Chang, L Li… - Chemical …, 2019 - ACS Publications
Development of biosensing platforms plays a key role in research settings for identification
of biomarkers and in clinical applications for diagnostics. Biosensors based on nucleic acids …

MicroRNA: function, detection, and bioanalysis

H Dong, J Lei, L Ding, Y Wen, H Ju, X Zhang - Chemical reviews, 2013 - ACS Publications
Mature microRNAs (miRNAs) are a class of evolutionally conserved, single-stranded, small
(approximately 19− 23 nucleotides), endogenously expressed, and non-protein-coding …

MicroRNAome genome: a treasure for cancer diagnosis and therapy

I Berindan‐Neagoe, PC Monroig… - CA: a cancer journal …, 2014 - Wiley Online Library
The interplay between abnormalities in genes coding for proteins and noncoding
microRNAs (miRNAs) has been among the most exciting yet unexpected discoveries in …

MiR-133b promotes neural plasticity and functional recovery after treatment of stroke with multipotent mesenchymal stromal cells in rats via transfer of exosome …

H Xin, Y Li, Z Liu, X Wang, X Shang, Y Cui… - Stem …, 2013 - academic.oup.com
To test, in vivo, the hypothesis that exosomes from multipotent mesenchymal stromal cells
(MSCs) mediate microRNA 133b (miR-133b) transfer which promotes neurological recovery …

Gold nanoparticles for biology and medicine

DA Giljohann, DS Seferos, WL Daniel… - Spherical Nucleic …, 2020 - api.taylorfrancis.com
Gold nanoparticles (AuNPs) have a rich history in chemistry, dating back to ancient R beg
glasses f an ov or decor er 150 y ati ears ago ve purpose oman times w s. The modern here …

In situ amplification‐based imaging of RNA in living cells

Z Qing, J Xu, J Hu, J Zheng, L He, Z Zou… - Angewandte …, 2019 - Wiley Online Library
Owing to its important physiological functions, especially as molecular biomarkers of
diseases, RNA is an important focus of biomedicine and biochemical sensing. Signal …

Toehold‐initiated rolling circle amplification for visualizing individual microRNAs in situ in single cells

R Deng, L Tang, Q Tian, Y Wang, L Lin… - Angewandte …, 2014 - Wiley Online Library
The ability to quantitate and visualize microRNAs (miRNAs) in situ in single cells would
greatly facilitate the elucidation of miRNA‐mediated regulatory circuits and their disease …