Roles of transposable elements in the regulation of mammalian transcription

R Fueyo, J Judd, C Feschotte, J Wysocka - Nature reviews Molecular …, 2022 - nature.com
Transposable elements (TEs) comprise about half of the mammalian genome. TEs often
contain sequences capable of recruiting the host transcription machinery, which they use to …

Ten things you should know about transposable elements

G Bourque, KH Burns, M Gehring, V Gorbunova… - Genome biology, 2018 - Springer
Transposable elements (TEs) are major components of eukaryotic genomes. However, the
extent of their impact on genome evolution, function, and disease remain a matter of intense …

Identifying transposable element expression dynamics and heterogeneity during development at the single-cell level with a processing pipeline scTE

J He, IA Babarinde, L Sun, S Xu, R Chen, J Shi… - Nature …, 2021 - nature.com
Transposable elements (TEs) make up a majority of a typical eukaryote's genome, and
contribute to cell heterogeneity in unclear ways. Single-cell sequencing technologies are …

An unbiased molecular approach using 3′-UTRs resolves the avian family-level tree of life

H Kuhl, C Frankl-Vilches, A Bakker… - Molecular Biology …, 2021 - academic.oup.com
Presumably, due to a rapid early diversification, major parts of the higher-level phylogeny of
birds are still resolved controversially in different analyses or are considered unresolvable …

TFs for TEs: the transcription factor repertoire of mammalian transposable elements

C Hermant, ME Torres-Padilla - Genes & development, 2021 - genesdev.cshlp.org
Transposable elements (TEs) are genetic elements capable of changing position within the
genome. Although their mobilization can constitute a threat to genome integrity, nearly half …

RNA m6A modification orchestrates a LINE-1–host interaction that facilitates retrotransposition and contributes to long gene vulnerability

F Xiong, R Wang, JH Lee, S Li, SF Chen, Z Liao… - Cell Research, 2021 - nature.com
The molecular basis underlying the interaction between retrotransposable elements (RTEs)
and the human genome remains poorly understood. Here, we profiled N 6-methyladenosine …

[HTML][HTML] Transposable elements are regulated by context-specific patterns of chromatin marks in mouse embryonic stem cells

J He, X Fu, M Zhang, F He, W Li, MM Abdul… - Nature …, 2019 - nature.com
The majority of mammalian genomes are devoted to transposable elements (TEs). Whilst
TEs are increasingly recognized for their important biological functions, they are a potential …

LINE-1 retrotransposons contribute to mouse PV interneuron development

GO Bodea, JM Botto, ME Ferreiro… - Nature …, 2024 - nature.com
Retrotransposons are mobile DNA sequences duplicated via transcription and reverse
transcription of an RNA intermediate. Cis-regulatory elements encoded by retrotransposons …

Transposable elements as new players in neurodegenerative diseases

C Ravel‐Godreuil, R Znaidi, T Bonnifet, RL Joshi… - FEBS …, 2021 - Wiley Online Library
Neurodegenerative diseases (NDs), including the most prevalent Alzheimer's disease and
Parkinson disease, share common pathological features. Despite decades of gene‐centric …

Regulatory transposable elements in the encyclopedia of DNA elements

AY Du, JD Chobirko, X Zhuo, C Feschotte… - Nature …, 2024 - nature.com
Abstract Transposable elements (TEs) comprise~ 50% of our genome, but knowledge of
how TEs affect genome evolution remains incomplete. Leveraging ENCODE4 data, we …