[HTML][HTML] Integrated neurophotonics: toward dense volumetric interrogation of brain circuit activity—at depth and in real time
We propose a new paradigm for dense functional imaging of brain activity to surmount the
limitations of present methodologies. We term this approach" integrated neurophotonics"; it …
limitations of present methodologies. We term this approach" integrated neurophotonics"; it …
Time for nanoneuro
A Garcia-Etxarri, R Yuste - Nature Methods, 2021 - nature.com
The study of electronic properties of materials at the nanoscale has unveiled physical laws
and generated materials such as nanoparticles, quantum dots, nanodiamonds …
and generated materials such as nanoparticles, quantum dots, nanodiamonds …
Optogenetic stimulation probes with single-neuron resolution based on organic LEDs monolithically integrated on CMOS
The use of optogenetic stimulation to evoke neuronal activity in targeted neural populations—
enabled by opsins with fast kinetics, high sensitivity and cell-type and subcellular specificity …
enabled by opsins with fast kinetics, high sensitivity and cell-type and subcellular specificity …
[HTML][HTML] Implantable photonic neural probes for light-sheet fluorescence brain imaging
WD Sacher, FD Chen, H Moradi-Chameh… - …, 2021 - spiedigitallibrary.org
Significance: Light-sheet fluorescence microscopy (LSFM) is a powerful technique for
highspeed volumetric functional imaging. However, in typical light-sheet microscopes, the …
highspeed volumetric functional imaging. However, in typical light-sheet microscopes, the …
Toward implantable devices for angle-sensitive, lens-less, multifluorescent, single-photon lifetime imaging in the brain using Fabry–Perot and absorptive color filters
Implantable image sensors have the potential to revolutionize neuroscience. Due to their
small form factor requirements; however, conventional filters and optics cannot be …
small form factor requirements; however, conventional filters and optics cannot be …
A subdural CMOS optical device for bidirectional neural interfacing
Optical neurotechnologies use light to interface with neurons and can monitor and
manipulate neural activity with high spatial-temporal precision over large cortical areas …
manipulate neural activity with high spatial-temporal precision over large cortical areas …
32× 64 SPAD imager using 2-bit in-pixel stack-based memory for low-light imaging
HH Huang, TY Huang, CH Liu, SD Lin… - IEEE Sensors …, 2023 - ieeexplore.ieee.org
This article presents a high-detection rate single-photon avalanche diode (SPAD) imaging
chip designed for photon-sensing applications. The test chip includes two essential design …
chip designed for photon-sensing applications. The test chip includes two essential design …
A Wireless, Multicolor Fluorescence Image Sensor Implant for Real-Time Monitoring in Cancer Therapy
Real-time monitoring of dynamic biological processes in the body is critical to understanding
disease progression and treatment response. These data, for instance, can help address the …
disease progression and treatment response. These data, for instance, can help address the …
Hybrid electrical and optical neural interfaces
Neural interfaces bridge the nervous system and the outside world by recording and
stimulating neurons. Combining electrical and optical modalities in a single, hybrid neural …
stimulating neurons. Combining electrical and optical modalities in a single, hybrid neural …
Subdural CMOS optical probe (SCOPe) for bidirectional neural interfacing
Optical neurotechnologies use light to interface with neurons and can monitor and
manipulate neural activity with high spatial-temporal precision over large cortical extents …
manipulate neural activity with high spatial-temporal precision over large cortical extents …