TET enzymes and 5hmC in adaptive and innate immune systems
DNA methylation is an abundant and stable epigenetic modification that allows inheritance
of information from parental to daughter cells. At active genomic regions, DNA methylation …
of information from parental to daughter cells. At active genomic regions, DNA methylation …
TET2 deficiency reprograms the germinal center B cell epigenome and silences genes linked to lymphomagenesis
The TET2 DNA hydroxymethyltransferase is frequently disrupted by somatic mutations in
diffuse large B cell lymphomas (DLBCLs), a tumor that originates from germinal center (GC) …
diffuse large B cell lymphomas (DLBCLs), a tumor that originates from germinal center (GC) …