Review on Experimental Treatment Strategies Against Trypanosoma cruzi

AL Mazzeti, P Capelari-Oliveira, MT Bahia… - Journal of …, 2021 - Taylor & Francis
Chagas disease is a neglected tropical disease caused by the protozoan Trypanosoma
cruzi. Currently, only nitroheterocyclic nifurtimox (NFX) and benznidazole (BNZ) are …

Drugs in preclinical and early clinical development for the treatment of Chagas´ s disease: the current status

FKVS Torchelsen, AL Mazzeti… - Expert Opinion on …, 2024 - Taylor & Francis
Introduction Chagas disease is spreading faster than expected in different countries, and
little progress has been reported in the discovery of new drugs to combat Trypanosoma cruzi …

Antiparasitic Effects of Asteraceae Species Extracts on Echinococcus granulosus ss

CM Albani, J Borgo, J Fabbri, P Pensel… - Evidence‐Based …, 2022 - Wiley Online Library
Cystic echinococcosis is a zoonotic disease caused by the parasite Echinococcus
granulosus sensu lato (sl), which is worldwide distributed and causes long‐lasting infections …

Sesquiterpene lactones and diterpenes: promising therapeutic candidates for infectious diseases, neoplasms and other chronic disorders

VP Sülsen - Molecules, 2021 - mdpi.com
Nature is an important source for the discovery of new bioactive compounds. Natural
compounds constitute a strategic starting point for the development of novel drugs, since …

Anthelmintic activity of Stevia multiaristata extract against Echinococcus granulosus sensu stricto

CM Albani, J Borgo, J Fabbri, P Pensel, L Fasciani… - Parasitology, 2022 - cambridge.org
Cystic echinococcosis is a zoonotic disease caused by the larval stage of the parasite
Echinococcus granulosus sensu lato. The available anti-parasitic treatment is mostly limited …

In silico toxicologic profile and in vivo trypanocidal activity of estafietin, a sesquiterpene lactone isolated from Stevia alpina Griseb.

OG Elso, N Cerny, LC Laurella, AE Bivona… - Natural Product …, 2024 - Taylor & Francis
Chagas disease is an infection caused by the protozoan Trypanosoma cruzi, affecting 6-8
million people worldwide. Only two drugs are available for its treatment, having a limited …

[PDF][PDF] O Trypanosoma cruzi EA DOENÇA DE CHAGAS

WD de Oliveira, VEP Santos, JG Crispim, AV Barbosa… - researchgate.net
O Trypanosoma cruzi é o agente causador da Doença de Chagas (DC) e apresenta maior
distribuição no continente americano. O presente capítulo de revisão apresenta as …