Cancer is one of the greatest threats facing our society, being the second leading cause of
death globally. Currents strategies for cancer diagnosis consist of the extraction of a solid …

Exosomes are extracellular vesicles released by many cell types and have been attributed
for their roles in many diseases including cancer. Exosomes secreted by tumor cells and …

RNA-based therapeutics hold great promise for treating diseases and lipid nanoparticles
(LNPs) represent the most advanced platform for RNA delivery. However, the fate of the LNP …

Extracellular vesicles (EVs) are transport vesicles secreted by living cells and released into
the extracellular environment. Recent studies have shown that EVs serve as “messengers” …

The RNA that is packaged into exosomes is termed as exosomal-shuttle RNA (esRNA);
however, the players, which take this subset of RNA (esRNA) into exosomes, remain largely …

Obesity is one of the main risk factors for type 2 diabetes mellitus (T2DM). It is closely related
to metabolic disturbances in the adipose tissue that primarily functions as a fat reservoir. For …

Extracellular vesicles (EVs) are membrane enclosed micro-and nano-sized vesicles that are
secreted from almost every species, ranging from prokaryotes to eukaryotes, and from …

Lipid nanoparticles (LNPs) are currently used to transport functional mRNAs, such as COVID‐
19 mRNA vaccines. The delivery of angiogenic molecules, such as therapeutic VEGF‐A …

One of the biggest challenges in the management of obesity is the prevention of weight
regain after successful weight loss. Weight regain after weight loss has large interindividual …

Chemotherapeutics continue to play a central role in the treatment of a wide variety of
cancers. Conventional chemotherapy involving bolus intravenous doses results in severe …