Nitro-oxidative stress and lowered antioxidant defences play a key role in neuropsychiatric
disorders such as major depression, bipolar disorder and schizophrenia. The first part of this …

Rationale Neuropsychiatric disorders encompass a broad category of medical conditions
that include both neurology as well as psychiatry such as major depressive disorder, autism …

Precise matching of energy substrate delivery to local metabolic needs is essential for the
health and function of all tissues. Here, we outline a mechanistic framework for …

Increasing spike rates drive greater neuronal energy demand. In turn, mitochondrial ATP
production leads to the generation of reactive oxygen species (ROS) that can modulate ion …

Previous studies from our laboratory have shown that the pressor response to
intracerebroventricular (icv) administered ANG II in normotensive rats or spontaneously …

Simultaneous analysis of hydrogen peroxide (H 2 O 2) and dopamine (DA) in central
nervous system is of great significance and has great challenges. Herein, we reported one …

Chronic intermittent hypoxia (CIH) is a model for obstructive sleep apnea. The
paraventricular nucleus (PVN) of the hypothalamus has been suggested to contribute to CIH …

Oxidative stress is one of the main proposed mechanisms involved in neuronal
degeneration. To evaluate the consequences of oxidative stress on motor cortex pyramidal …

It has been reported that reactive oxygen species (ROS) derived from oxygen molecule
reduction can interfere with the cross-talk between the hypothalamic-pituitary-gonadal …

Neuronal KV 7 channels, important regulators of cell excitability, are among the most
sensitive proteins to reactive oxygen species. The S2S3 linker of the voltage sensor was …