Diffusion tensor imaging (DTI) allows the in vivo imaging of pathological white matter
alterations, either with unbiased voxel-wise or hypothesis-guided tract-based analysis …

Disease heterogeneity in amyotrophic lateral sclerosis poses a substantial challenge in drug
development. Categorization based on clinical features alone can help us predict the …

Background The characterisation of presymptomatic disease-burden patterns in
asymptomatic mutation carriers has a dual academic and clinical relevance. The …

The nomenclature of amyotrophic lateral sclerosis (ALS) currently is blurred, indistinct and
no accurate and haven't been properly updated since the first description, which is far from …

Simple Summary Amyotrophic lateral sclerosis (ALS) is the most common form of Motor
Neuron Disease and is traditionally associated with motor cortex, brainstem and spinal cord …

Background and objective The neuropathology of amyotrophic lateral sclerosis (ALS)
follows a regional distribution pattern in the brain with four stages. Using diffusion tensor …

Neuroimaging biomarkers have shown high potential to map the disease processes in the
application to neurodegenerative diseases (NDD), eg, diffusion tensor imaging (DTI). For …

In practical applications, Bayesian classification methods have been successfully employed.
The Naïve Bayes algorithm (NB) is a quick, successful, and well-known Bayesian …

Despite the universal recognition of the fundamental clinical, genetic and pathological
heterogeneity of amyotrophic lateral sclerosis (ALS), the expectation that the same drug may …

The distinct clinical and radiological characteristics of right temporal variant FTD have only
been recently recognized. Methods: Eight patients with right temporal variant FTD were …