Metabolomics as a valid analytical technique in environmental exposure research: application and progress

S Wei, Y Wei, Y Gong, Y Chen, J Cui, L Li, H Yan, Y Yu… - Metabolomics, 2022 - Springer
Background In recent years, studies have shown that exposure to environmental pollutants
(eg, radiation, heavy metal substances, air pollutants, organic pollutants) is a leading cause …

Vitamin D, gut microbiota, and radiation-related resistance: a love-hate triangle

R Huang, J Xiang, P Zhou - Journal of Experimental & Clinical Cancer …, 2019 - Springer
Radiation resistance is a serious issue in radiotherapy. Increasing evidence indicates that
the human gut microbiome plays a role in the development of radiation resistance. Vitamin D …

Oxidative modifications in tissue pathology and autoimmune disease

ML Yang, HA Doyle, SG Clarke, KC Herold… - Antioxidants & redox …, 2018 - liebertpub.com
Significance: Various autoimmune syndromes are characterized by abnormalities found at
the level of tissues and cells, as well as by microenvironmental influences, such as reactive …

A systematic review of metabolomic and lipidomic candidates for biomarkers in radiation injury

E Vicente, Z Vujaskovic, IL Jackson - Metabolites, 2020 - mdpi.com
A large-scale nuclear event has the ability to inflict mass casualties requiring point-of-care
and laboratory-based diagnostic and prognostic biomarkers to inform victim triage and …

Dose–response curves for analyzing of dicentric chromosomes and chromosome translocations following doses of 1000 mGy or less, based on irradiated peripheral …

Y Abe, MA Yoshida, K Fujioka, Y Kurosu… - Journal of radiation …, 2018 - academic.oup.com
In terms of biological dosimetry at the time of radiation exposure, the dicentric chromosome
(Dic) assay (DCA) is the gold standard for assessing for the acute phase and chromosome …

Citrulline, a potential biomarker of radiation-induced small intestine damage

F Ye, J Ning, Z Fardous, T Katsube, Q Li… - Dose …, 2020 - journals.sagepub.com
Radiation damage assessment of the small intestine is important in nuclear accidents or
routine radiotherapy of abdominal tumors. This article reviews the clinical symptoms and …

Differential mobility spectrometry-mass spectrometry (DMS-MS) in radiation biodosimetry: Rapid and high-throughput quantitation of multiple radiation biomarkers in …

Z Chen, SL Coy, EL Pannkuk, EC Laiakis… - Journal of the …, 2018 - ACS Publications
High-throughput methods to assess radiation exposure are a priority due to concerns that
include nuclear power accidents, the spread of nuclear weapon capability, and the risk of …

Identification of potential radiation responsive metabolic biomarkers in plasma of rats exposed to different doses of cobalt-60 gamma rays

H Zhao, C Xi, M Tian, X Lu, TJ Cai, S Li… - Dose …, 2020 - journals.sagepub.com
Metabolomics has great potential to process accessible biofluids through high-throughput
and quantitative analysis for radiation biomarker screening. This study focused on the …

Metabolomics reveals dose effects of low-dose chronic exposure to uranium in rats: identification of candidate biomarkers in urine samples

S Grison, G Favé, M Maillot, L Manens, O Delissen… - Metabolomics, 2016 - Springer
Introduction Data are sparse about the potential health risks of chronic low-dose
contamination of humans by uranium (natural or anthropogenic) in drinking water. Previous …

Urinary metabolic signatures and early triage of acute radiation exposure in rat model

M Zhao, KKT Lau, X Zhou, J Wu, J Yang… - Molecular …, 2017 - pubs.rsc.org
After a large-scale radiological accident, early-response biomarkers to assess radiation
exposure over a broad dose range are not only the basis of rapid radiation triage, but are …