Formulation of poloxamers for drug delivery

AM Bodratti, P Alexandridis - Journal of functional biomaterials, 2018 - mdpi.com
Poloxamers, also known as Pluronics®, are block copolymers of poly (ethylene oxide)(PEO)
and poly (propylene oxide)(PPO), which have an amphiphilic character and useful …

Enabling future nanomanufacturing through block copolymer self-assembly: A review

C Cummins, R Lundy, JJ Walsh, V Ponsinet, G Fleury… - Nano Today, 2020 - Elsevier
Self-assembly approaches, eg colloidal, emulsion and polymer phase separation, provide
scientists with an exotic yet direct platform to access technologically desired nanostructures …

PEG-PCL-based nanomedicines: A biodegradable drug delivery system and its application

P Grossen, D Witzigmann, S Sieber… - Journal of Controlled …, 2017 - Elsevier
The lack of efficient therapeutic options for many severe disorders including cancer spurs
demand for improved drug delivery technologies. Nanoscale drug delivery systems based …

Polymeric micelles for anticancer drug delivery

N Majumder, NG Das, SK Das - Therapeutic delivery, 2020 - Taylor & Francis
Polymeric micelles have gained interest as novel drug delivery systems for the treatment
and diagnosis of cancer, as they offer several advantages over conventional drug therapies …

Polymeric micelles as drug delivery vehicles

Z Ahmad, A Shah, M Siddiq, HB Kraatz - Rsc Advances, 2014 - pubs.rsc.org
Though much progress has been made in drug delivery systems, the design of a suitable
carrier for the delivery of hydrophobic drugs is still a major challenge for researchers. The …

Advanced materials and processing for drug delivery: the past and the future

Y Zhang, HF Chan, KW Leong - Advanced drug delivery reviews, 2013 - Elsevier
Design and synthesis of efficient drug delivery systems are of vital importance for medicine
and healthcare. Materials innovation and nanotechnology have synergistically fueled the …

Polymeric micelles and alternative nanonized delivery vehicles for poorly soluble drugs

Y Lu, K Park - International journal of pharmaceutics, 2013 - Elsevier
Poorly soluble drugs often encounter low bioavailability and erratic absorption patterns in
the clinical setting. Due to the rising number of compounds having solubility issues, finding …

Micellization of poly (ethylene oxide)-poly (propylene oxide)-poly (ethylene oxide) triblock copolymers in aqueous solutions: thermodynamics of copolymer association

P Alexandridis, JF Holzwarth, TA Hatton - Macromolecules, 1994 - ACS Publications
The critical micellization temperature (cmt) and critical micellization concentration (cmc)
values of 12 Plutonic polyethylene oxide)-poly (propylene oxide)-poly (ethylene oxide)(PEO …

Poly (ethylene oxide) poly (propylene oxide) poly (ethylene oxide) block copolymer surfactants in aqueous solutions and at interfaces: thermodynamics, structure …

P Alexandridis, TA Hatton - Colloids and Surfaces A: Physicochemical and …, 1995 - Elsevier
The association properties of poly (ethylene oxide)-block-poly (propyleneoxide)-block-poly
(ethylene oxide)(PEO PPO PEO) copolymers (commercially available as Poloxamers …

Structure and design of polymeric surfactant-based drug delivery systems

VP Torchilin - Journal of controlled release, 2001 - Elsevier
The review concentrates on the use of polymeric micelles as pharmaceutical carriers.
Micellization of biologically active substances is a general phenomenon that increases the …