Genetic Effects of Single Nucleotide Polymorphisms in the Goat GDF9 Gene on Prolificacy: True or False Positive?

X Wang, Q Yang, S Zhang, X Zhang, C Pan, H Chen… - Animals, 2019 - mdpi.com
Simple Summary As an important regulator factor, which was secreted by female oocytes,
the growth differentiation factor 9 (GDF9) plays an essential role during the growth and …

Goat membrane associated ring-CH-type finger 1 (MARCH1) mRNA expression and association with litter size

Z Kang, E Jiang, K Wang, C Pan, H Chen, H Yan… - Theriogenology, 2019 - Elsevier
Membrane-associated ring-CH-type finger 1 (MARCH1), which mediates the ubiquitination
of CD86 and MHC class II proteins, plays crucial roles in ruminant fecundity. To completely …

Effect of CTSS non-synonymous mutations on litter size in Qianbei Ma goats

Y Zhang, X Chen, Y Ruan, W Guo, J Chen… - Frontiers in Veterinary …, 2023 - frontiersin.org
Cathepsin S (CTSS) is a member of the cysteine protease family closely related to
reproductive regulation in goats. However, its effect on litter size in goats remains unclear. In …

Analysis of goat PPP6C mRNA profile, detection of genetic variations, and their associations with litter size

Y Bai, D Bo, Y Bi, E Areb, H Zhu, C Pan… - Animal Reproduction …, 2024 - Elsevier
Abstract The Protein Phosphatase 6 Catalytic Subunit (PPP6C) is evolutionarily a conserved
gene in eukaryotes known to play a significant role in mammalian reproduction. This study …

Excessive nerve growth factor impairs bidirectional communication between the oocyte and cumulus cells resulting in reduced oocyte competence

Y Zhai, G Yao, F Rao, Y Wang, X Song… - Reproductive Biology and …, 2018 - Springer
Background Excessive nerve growth factor (NGF) is commonly found in the follicular fluid of
patients with polycystic ovary syndrome (PCOS). Furthermore, oocytes from PCOS patients …

Sirtuin3 (SIRT3) gene molecular characterization and SNP detection in prolific and low prolific goat breeds

MV Silpa, T Naicy, TV Aravindakshan, G Radhika… - Theriogenology, 2018 - Elsevier
Abstract Sirtuin3 (SIRT3) is a member of the Sirtuin family of NAD+-dependent deacetylase.
They have evolved as a vital protein in preventing the activation of reactive oxygen species …

[HTML][HTML] Potential Candidate Genes Associated with Litter Size in Goats: A Review

W Chen, Y Han, Y Chen, X Liu, H Liang… - Animals: an Open …, 2025 - pmc.ncbi.nlm.nih.gov
This review examines genetic markers associated with litter size in goats, a key reproductive
trait impacting productivity in small ruminant farming. Goats play a vital socioeconomic role …

Litter Size of Sheep (Ovis aries): Inbreeding Depression and Homozygous Regions

L Tao, X He, X Wang, R Di, M Chu - Genes, 2021 - mdpi.com
Ovine litter size (LS) is an important trait showing variability within breeds. It remains largely
unknown whether inbreeding depression on LS exists based on genomic homozygous …

Characterization of a 7 bp indel in MARCH1 promoter associated with reproductive traits in Malabari and Attappady Black goats of India

AG Desai, T Naicy, TV Aravindakshan… - Small Ruminant …, 2021 - Elsevier
Membrane-associated RING CH-type finger 1 (MARCH1) gene belongs to a family member
of RING-v type E3 ubiquitin ligases, which consists of 11 known members, some of which …

Association of a SacII polymorphism in the Nerve Growth Factor (NGF) gene exon 3 with growth traits in Indian goats

T Naicy, T Venkatachalapathy, TV Aravindakshan… - Small ruminant …, 2018 - Elsevier
Abstract Nerve Growth Factor expression in skeletal muscle tissue is associated with an
autocrine action by its effect on the proliferation, fusion into myotubes and morphology of …