It's Not Easy Being Green: A Narrative Review on the Microbiology, Virulence and Therapeutic Prospects of Multidrug-Resistant Pseudomonas aeruginosa

P Behzadi, Z Baráth, M Gajdács - Antibiotics, 2021 - mdpi.com
Pseudomonas aeruginosa is the most frequent cause of infection among non-fermenting
Gram-negative bacteria, predominantly affecting immunocompromised patients, but its …

Advancement of gallium and gallium-based compounds as antimicrobial agents

F Li, F Liu, K Huang, S Yang - Frontiers in bioengineering and …, 2022 - frontiersin.org
With the abuse and misuse of antibiotics, antimicrobial resistance has become a challenging
issue in the medical system. Iatrogenic and non-iatrogenic infections caused by multidrug …

[HTML][HTML] Gallium and gallium compounds: New insights into the “Trojan horse” strategy in medical applications

W Sun, M Qi, S Cheng, C Li, B Dong, L Wang - Materials & Design, 2023 - Elsevier
Infection, inflammation, tumors, and other illnesses have for a long time posed a major
danger to human health and have developed into a global public health issue. However, the …

Gallium-enabled bactericidal medicine

Y Liu, F Yang, Z Pan, Z Fu, X Jiang, Z Cao, J Li… - Materials Today, 2023 - Elsevier
Metallic materials have been used as antibacterial agents since antiquity. Gallium (Ga), an
abiogenic metal, has shown pharmaceutical effects in developing unconventional …

Based on multi-omics technology study the antibacterial mechanisms of pH-dependent N-GQDs beyond ROS

W Wu, Y Qin, Y Fang, Y Zhang, S Shao, F Meng… - Journal of Hazardous …, 2023 - Elsevier
Currently, graphene quantum dots (GQDs) are widely used as antibacterial agents, and their
effects are dependent on the reactive oxygen species (ROS) generated by photodynamic …

Host-bacterial pathogen communication: the wily role of the multidrug efflux pumps of the MFS family

M Pasqua, MC Bonaccorsi di Patti, G Fanelli… - Frontiers in Molecular …, 2021 - frontiersin.org
Bacterial pathogens are able to survive within diverse habitats. The dynamic adaptation to
the surroundings depends on their ability to sense environmental variations and to respond …

A 3D printed Ga containing scaffold with both anti-infection and bone homeostasis-regulating properties for the treatment of infected bone defects

M Wang, Y Yang, G Chi, K Yuan, F Zhou… - Journal of Materials …, 2021 - pubs.rsc.org
Large bone defects face a high risk of infection, which can also lead to bone homeostasis
disorders. This seriously hinders the bone healing process; therefore, the help of a dual …

Advantageous reactivity of unstable metal complexes: Potential applications of metal-based anticancer drugs for intratumoral injections

A Levina, DC Crans, PA Lay - Pharmaceutics, 2022 - mdpi.com
Injections of highly cytotoxic or immunomodulating drugs directly into the inoperable tumor is
a procedure that is increasingly applied in the clinic and uses established Pt-based drugs. It …

Adaptive laboratory evolution of Salmonella enterica in acid stress

M Ghoshal, TD Bechtel, JG Gibbons… - Frontiers in …, 2023 - frontiersin.org
Introduction Adaptive laboratory evolution (ALE) studies play a crucial role in understanding
the adaptation and evolution of different bacterial species. In this study, we have …

EvgS/EvgA, the unorthodox two-component system regulating bacterial multiple resistance

R Zhang, Y Wang - Applied and Environmental Microbiology, 2023 - Am Soc Microbiol
Two-component systems (TCSs) widely exist in bacteria and assist bacteria in adjusting
behaviors to adapt to environmental changes after sensing environmental signals and …