The liver is known to be involved in the natural history of the ongoing epidemics of type 2
diabetes mellitus and cardiovascular disease. In particular, the liver has a role in increased …

The final step of biomineralization is a chemical precipitation reaction that occurs
spontaneously in supersaturated or metastable salt solutions. Genetic programs direct …

Type 2 diabetes and cardiovascular disease represent a serious threat to the health of the
population worldwide. Although overall adiposity and particularly visceral adiposity are …

Fetuin inhibits insulin-induced insulin receptor (IR) autophosphorylation and tyrosine kinase
activity in vitro, in intact cells, and in vivo. The fetuin gene (AHSG) is located on human …

Context Fetuin-A is a hepatic secretory protein that binds the insulin receptor and inhibits
insulin action in vitro. In prior cross-sectional studies in humans, higher fetuin-A levels were …

Sixty-six years have elapsed since the discovery of fetuin in 1944, but its importance in
mammalian physiology has only recently been appreciated. Fetuin, first isolated from fetal …

Background—Fetuin-A is a multifunctional hepatic secretory protein that inhibits the action of
insulin in experimental animals. We evaluated the association between human serum fetuin …

Background The secreted liver protein fetuin-A (AHSG) is up-regulated in hepatic steatosis
and the metabolic syndrome. These states are strongly associated with low-grade …

Fetuin-A (FetA) is a 64-kDa glycoprotein that is secreted from both the liver and adipose
tissue. Circulating FetA is elevated in obesity and related disorders including type 2 diabetes …

Alpha 2-Heremans-Schmid glycoprotein, also known as fetuin-A (Fet-A), is a multifunctional
plasma glycoprotein that has been identified in both animal and human beings. The protein …