The bacterial thiopeptide thiostrepton. An update of its mode of action, pharmacological properties and applications

C Bailly - European Journal of Pharmacology, 2022 - Elsevier
The bacterial thiopeptide thiostrepton (TS) is used as a veterinary medicine to treat bacterial
infections. TS is a protein translation inhibitor, essentially active against Gram-positive …

Critical examination of approaches exploited to assess the effectiveness of transmission-blocking drugs for malaria

I Wadi, AR Anvikar, M Nath, CR Pillai… - Future medicinal …, 2018 - Taylor & Francis
In the absence of clinically proven vaccines and emerging resistance to common
antimalarials and insecticides, the onus of interrupting the life cycle of Plasmodium …

[HTML][HTML] Inhibitory effect of dihydroartemisinin on chondrogenic and hypertrophic differentiation of mesenchymal stem cells

Z Cao, C Liu, Y Bai, C Dou, JM Li, DW Shi… - American Journal of …, 2017 - ncbi.nlm.nih.gov
Chondrocytes located in hyaline cartilage may maintain phenotype while the chondrocytes
situated in calcified cartilage differentiate into hypertrophy. Chondrogenic and hypertrophic …

High-Throughput Screen Identifying the Thiosemicarbazone NSC319726 Compound as a Potent Antimicrobial Lead Against Resistant Strains of Escherichia coli

C Sadaka, P Damborg, JL Watts - Biomolecules, 2018 - mdpi.com
Antibiotic discovery is vital when considering the increasing antimicrobial resistance threat.
The aim of this work was to provide a high-throughput screen (HTS) assay using multidrug …

Etude de l'hémozoïne des gamétocytes de Plasmodium falciparum et impact de la ganaplacide

R Omorou - 2023 - theses.hal.science
Le paludisme, un problème de santé publique persistant malgré les efforts de lutte, continue
de faire des centaines de milliers de morts par an. Face à la résistance croissante des …

Gametocyte and malaria transmission.

N Piaraksa, Y Singhaboot, S Keayarsa… - 2017 - cabidigitallibrary.org
Prevention of malaria transmission from human to mosquitoes is one of the crucial factors
required for malaria elimination. Gametocytes representing the sexual erythrocytic stage of …

[图书][B] Exploring the Kinase Inhibitor Chemical Space for Novel Dual Active and Gametocyte-focussed Antimalarials

ME Van der Watt - 2018 - search.proquest.com
The success achieved in controlling malaria in recent years [1, 2], has caused a focal shift to
elimination of the disease, with renewed interest in the discovery of novel …