Inherited retinal diseases (IRDs) are at the forefront of innovative gene-specific treatments
because of the causation by single genes, the availability of microsurgical access for …

This presentation will survey the retinal architecture, advantages, and limitations of several
lesser-known rodent species that provide a useful diurnal complement to rats and mice …

Purpose: To quantify organelles impacting imaging in the cell body and intact apical
processes of human retinal pigment epithelium (RPE), including melanosomes, lipofuscin …

Purpose: Despite the centrality of the retinal pigment epithelium (RPE) in vision and
retinopathy our picture of RPE morphology is incomplete. With a volumetric reconstruction of …

Tree shrews are small mammals with excellent vision and are closely related to primates.
They have been used extensively as a model for studying refractive development, myopia …

Mitochondria are candidate reflectivity signal sources in optical coherence tomography
(OCT) retinal imaging. Here, we use deep-learning-assisted volume electron microscopy of …

In vitro differentiation of human pluripotent stem cells (hPSCs) into specialized tissues and
organs represents a powerful approach to gain insight into those cellular and molecular …

Cone photoreceptors of the 13-lined ground squirrel (13-LGS) undergo reversible structural
changes during hibernation, including cone outer segment disc degeneration and inner …

Purpose: The purpose of this study is to assess with spectral-domain optical coherence
tomography (OCT) the interspecies variation of outer retinal morphology and identification of …

The great evolutionary biologist, Theodosius Dobzhansky, once said,“Nothing in biology
makes sense except in the light of evolution.” Vision, no doubt, is a poster child for the work …