Voltage-gated calcium channels are required for many key functions in the body. In this
review, the different subtypes of voltage-gated calcium channels are described and their …

Voltage-gated calcium channels are the primary mediators of depolarization-induced
calcium entry into neurons. There is great diversity of calcium channel subtypes due to …

Voltage-gated calcium channels are important regulators of brain, heart and muscle
functions, and their dysfunction can give rise to pathophysiological conditions ranging from …

Migraine is a common, disabling, and undertreated episodic brain disorder that is more
common in women than in men. Unbiased genome-wide association studies have identified …

This review summarizes our current knowledge of human disease-relevant genetic variants
within the family of voltage gated Ca2+ channels. Ca2+ channelopathies cover a wide …

Voltage-gated calcium channels (VGCCs) are widely expressed in the brain, heart and
vessels, smooth and skeletal muscle, as well as in endocrine cells. VGCCs mediate gene …

Voltage-gated calcium channels (VGCCs) are targeted to treat pain conditions. Since the
discovery of their relation to pain processing control, they are investigated to find new …

Voltage-gated Na and Ca2+ channels represent two major ion channel families that enable
myriad biological functions including the generation of action potentials and the coupling of …

Human mutations in the CACNA1A gene that encodes the pore-forming α 1A subunit of the
voltage-gated Ca V 2.1 (P/Q-type) Ca 2+ channel cause multiple neurological disorders …

Synaptic transmission is a fundamental neurobiological process enabling exchange of
signals between neurons as well as neurons and their non-neuronal effectors. The complex …