Non-invasive biomarkers for early detection of breast cancer

J Li, X Guan, Z Fan, LM Ching, Y Li, X Wang, WM Cao… - Cancers, 2020 - mdpi.com
Simple Summary Early diagnosis of breast cancer greatly increases the chance of cure and
survival from the disease. The mammogram is widely used for early detection of breast …

Droplet-based digital PCR and next generation sequencing for monitoring circulating tumor DNA: a cancer diagnostic perspective

M Postel, A Roosen, P Laurent-Puig… - Expert review of …, 2018 - Taylor & Francis
Introduction: Early detection of cancers through the analysis of ctDNA could have a
significant impact on morbidity and mortality of cancer patients. However, using ctDNA for …

An immune-related gene prognostic index for head and neck squamous cell carcinoma

Y Chen, ZY Li, GQ Zhou, Y Sun - Clinical Cancer Research, 2021 - AACR
Purpose: To construct an immune-related gene prognostic index (IRGPI) for head and neck
squamous cell carcinoma (HNSCC) and clarify the molecular and immune characteristics …

Evolutionary histories of breast cancer and related clones

T Nishimura, N Kakiuchi, K Yoshida, T Sakurai… - Nature, 2023 - nature.com
Recent studies have documented frequent evolution of clones carrying common cancer
mutations in apparently normal tissues, which are implicated in cancer development …

Breast cancer; discovery of novel diagnostic biomarkers, drug resistance, and therapeutic implications

S Afzal, M Hassan, S Ullah, H Abbas… - Frontiers in molecular …, 2022 - frontiersin.org
Breast cancer is the second most reported cancer in women with high mortality causing
millions of cancer-related deaths annually. Early detection of breast cancer intensifies the …

Current and emerging applications of droplet digital PCR in oncology

S Olmedillas-López, M García-Arranz… - Molecular diagnosis & …, 2017 - Springer
The clinical management of cancer has evolved in recent years towards more personalized
strategies that require a comprehensive knowledge of the complex molecular features …

Detection and relevance of epigenetic markers on ctDNA: recent advances and future outlook

E Lianidou - Molecular Oncology, 2021 - Wiley Online Library
Liquid biopsy, a minimally invasive approach, is a highly powerful clinical tool for the real‐
time follow‐up of cancer and overcomes many limitations of tissue biopsies. Epigenetic …

Identifying DNA methylation biomarkers for non-endoscopic detection of Barrett's esophagus

HR Moinova, T LaFramboise, JD Lutterbaugh… - Science translational …, 2018 - science.org
We report a biomarker-based non-endoscopic method for detecting Barrett's esophagus
(BE) based on detecting methylated DNAs retrieved via a swallowable balloon-based …

Integrative analysis of multi-omics data for liquid biopsy

G Chen, J Zhang, Q Fu, V Taly, F Tan - British journal of cancer, 2023 - nature.com
The innovation of liquid biopsy holds great potential to revolutionise cancer management
through early diagnosis and timely treatment of cancer. Integrative analysis of different …

A serum-based DNA methylation assay provides accurate detection of glioma

TS Sabedot, TM Malta, J Snyder, K Nelson… - Neuro …, 2021 - academic.oup.com
Background The detection of somatic mutations in cell-free DNA (cfDNA) from liquid biopsy
has emerged as a noninvasive tool to monitor the follow-up of cancer patients. However, the …