In the past 4 years, many publications described a concentration-dependent deposition of
gadolinium in the brain both in adults and children, seen as high signal intensities in the …

Gadolinium-based contrast agents (GBCAs) are commonly used for enhancement in MR
imaging and have long been considered safe when administered at recommended doses …

For magnetic resonance, the established class of intravenous contrast media is the
gadolinium-based contrast agents. In the 3 decades since initial approval, these have …

No discussion of challenges for chemistry in molecular imaging would be complete without
addressing the elephant in the room—which is that the purest of chemical compounds …

Ever since gadolinium was found to deposit in the brain of patients with normal kidney
function by Kanda et al. in 2014, several studies have been conducted to evaluate its effect …

Objectives The aim of this study was to determine in vivo if brain inflammation leads to
increased gadolinium (Gd) retention in brain tissue after repeated applications of Gd-based …

MRI is widely used in clinical practice for detecting liver diseases. Since the introduction of
gadoxetic acid, MRI has become the most effective modality for the detection and …

Objective The aim of this study was to evaluate and compare changes in T1-weighted signal
intensity (SI) within the dentate nucleus (DN) and globus pallidus (GP) in a pediatric …

After the initial report in 2014 on T1-weighted (T1w) hyperintensity of deep brain nuclei
following serial injections of linear gadolinium-based contrast agents (GBCAs), a multitude …

Since its introduction in the worldwide medical market, gadoxetic acid has attracted
considerable interest. The year 2023 marks the 15th anniversary of the introduction of …