Stroke remains a leading cause of death and disability, with limited therapeutic options and
suboptimal tools for diagnosis and prognosis. High throughput technologies such as …

Adaptor proteins play central roles in the assembly of molecular complexes and co-
ordinated activation of specific pathways. Through their modular domain structure, the NCK …

Women are at a significantly higher risk of developing osteoarthritis (OA) compared to
males. The pathogenesis of osteoarthritis (OA) in women is poorly understood. Extracellular …

Background In this study, we aimed to combine transcriptomic and network pharmacology to
explore the crucial mRNAs and specific regulatory molecules of Buyang Huanwu Decoction …

Protein posttranslational modifications (PTMs) regulate the biological processes of human
diseases by genetic code expansion and cellular pathophysiology regulation; however …

Intracranial hemorrhage (ICH) is a devastating disorder. Neuroprotective strategies that
prevent tissue injury and improve functional outcomes have been identified in multiple …

Intracerebral hemorrhage (ICH) or hemorrhagic stroke is a major public health problem with
no effective treatment. Given the emerging role of epigenetic mechanisms in the …

Background Intracerebral hemorrhage (ICH) is the top lethal and disabling form of stroke.
The pathophysiology of ICH is not fully understood yet. Metabolites are indicators and …

Objective: To study the effect of PPARγ agonist (rosiglitazone) on the polarization of
microglia around the hematoma after intracerebral hemorrhage in male SD rats. Materials …