TFOS DEWS II clinical trial design report

GD Novack, P Asbell, S Barabino, MVW Bergamini… - The ocular …, 2017 - Elsevier
The development of novel therapies for Dry Eye Disease (DED) is formidable, and relatively
few treatments evaluated have been approved for marketing. In this report, the …

Discriminant analysis and binary logistic regression enable more accurate prediction of autism spectrum disorder than principal component analysis

WM Hassan, A Al-Dbass, L Al-Ayadhi, RS Bhat… - Scientific Reports, 2022 - nature.com
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by
impaired social interaction and restricted, repetitive behavior. Multiple studies have …

Challenges in using signs and symptoms to evaluate new biomarkers of dry eye disease

B Sullivan - The ocular surface, 2014 - Elsevier
The lack of association between signs and symptoms in dry eye disease (DED) 1, 2, 3, 4
presents a challenge in designing clinical trials to objectively evaluate the performance of …

Bee Pollen and Probiotics May alter brain neuropeptide levels in a Rodent Model of Autism Spectrum disorders

MA Alghamdi, L Al-Ayadhi, WM Hassan, RS Bhat… - Metabolites, 2022 - mdpi.com
Neuropeptides play a major role in maintaining normal brain development in children.
Dysfunction of some specific neuropeptides can lead to autism spectrum disorders (ASD) in …

Randomized, masked, in vitro comparison of three commercially available tear film osmometers

G Rocha, E Gulliver, A Borovik, CC Chan - Clinical Ophthalmology, 2017 - Taylor & Francis
Purpose The purpose of this study was to compare the precision and accuracy of
commercially available tear film osmometers. Methods Contrived tear solution target values …

[HTML][HTML] Long-term tear volume changes after blepharoptosis surgery and blepharoplasty

A Watanabe, D Selva, H Kakizaki, Y Oka… - … & Visual Science, 2015 - arvojournals.org
Purpose.: To evaluate long-term changes in tear volume by using video meniscometry
following blepharoptosis surgery and upper blepharoplasty. Methods.: Forty-three eyes of 27 …

Effectiveness of acupuncture combined with artificial tears in managing dry eye syndrome: A systematic review and meta-analysis

Y Wang, J Peng, L Xiao, Y Deng, J Lu, YS Zhou… - Medicine, 2024 - journals.lww.com
Background: Dry eye syndrome is an ocular surface disease with high incidence.
Acupuncture combined with artificial tears is effective for treating dry eye syndrome. This …

The use of multi-parametric biomarker profiles may increase the accuracy of ASD prediction

WM Hassan, L Al-Ayadhi, G Bjørklund… - Journal of Molecular …, 2018 - Springer
Effective biomarkers are urgently needed to facilitate early diagnosis of autism spectrum
disorder (ASD), permitting early intervention, and consequently improving prognosis. In this …

Screening for dry eye disease using infrared ocular thermography

LL Tan, S Sanjay, PB Morgan - Contact Lens and Anterior Eye, 2016 - Elsevier
Purpose To evaluate the efficacy of infrared (IR) ocular thermography in screening for dry
eye disease (DED). Methods IR ocular thermography was performed on 62 dry eye and 63 …

Changes of ocular surface and the inflammatory response in a rabbit model of short-term exposure keratopathy

CT Lai, WC Yao, SY Lin, HY Liu, HW Chang, FR Hu… - PLoS …, 2015 - journals.plos.org
Purpose To evaluate the ocular surface change and the inflammatory response in a rabbit
model of short-term exposure keratopathy. Methods Short term exposure keratopathy by …