Biofilm-related disease

JL Del Pozo - Expert review of anti-infective therapy, 2018 - Taylor & Francis
Introduction: Biofilm formation represents a protected mode of growth that renders bacterial
cells less susceptible to antimicrobials and to killing by host immune effector mechanisms …

Antimicrobial peptides and wound healing: biological and therapeutic considerations

ML Mangoni, AM McDermott… - Experimental …, 2016 - Wiley Online Library
Repair of tissue wounds is a fundamental process to re‐establish tissue integrity and regular
function. Importantly, infection is a major factor that hinders wound healing. Multicellular …

The limitations of in vitro experimentation in understanding biofilms and chronic infection

AEL Roberts, KN Kragh, T Bjarnsholt… - Journal of Molecular …, 2015 - Elsevier
We have become increasingly aware that, during infection, pathogenic bacteria often grow
in multicellular biofilms that are often highly resistant to antibacterial strategies. In order to …

Challenges and innovations in treating chronic and acute wound infections: from basic science to clinical practice

X Ding, Q Tang, Z Xu, Y Xu, H Zhang, D Zheng… - Burns & …, 2022 - academic.oup.com
Acute and chronic wound infection has become a major worldwide healthcare burden
leading to significantly high morbidity and mortality. The underlying mechanism of infections …

Advances in the sensing and treatment of wound biofilms

S Darvishi, S Tavakoli, M Kharaziha… - Angewandte …, 2022 - Wiley Online Library
Wound biofilms represent a particularly challenging problem in modern medicine. They are
increasingly antibiotic resistant and can prevent the healing of chronic wounds. However …

Optimized scratch assay for in vitro testing of cell migration with an automated optical camera

MV Mouritzen, H Jenssen - Journal of visualized experiments …, 2018 - pmc.ncbi.nlm.nih.gov
Cell migration is an important process that influences many aspects of health, such as
wound healing and cancer, and it is, therefore, crucial for developing methods to study the …

[HTML][HTML] Comparative analysis of electrochemical and optical sensors for detection of chronic wounds biomarkers: A review

FAR Mota, MLC Passos, JLM Santos… - Biosensors and …, 2024 - Elsevier
Chronic wounds (CW) present a significant healthcare challenge due to their prolonged
healing time and associated complications. To effectively treat these wounds and prevent …

Biofilm-derived oxylipin 10-HOME–mediated immune response in women with breast implants

I Khan, RE Minto, C Kelley-Patteson… - The Journal of …, 2024 - Am Soc Clin Investig
This study investigates a mechanistic link of bacterial biofilm–mediated host-pathogen
interaction leading to immunological complications associated with breast implant illness …

Hard-to-heal wounds, biofilm and wound healing: An intricate interrelationship

MM Azevedo, C Lisboa, L Cobrado… - British Journal of …, 2020 - magonlinelibrary.com
Hard-to-heal wounds are a major public health problem that incur high economic costs. A
major source of morbidity, they can have an overwhelming impact on patients, caregivers …

Sample procurement for cultures of infected wounds: a systematic review

LR Copeland-Halperin, AJ Kaminsky… - Journal of wound …, 2016 - magonlinelibrary.com
Objective: Identifying the responsible pathogen is required in order to select optimum
antimicrobial therapy for infected wounds, but the best techniques to use remain the subject …