Background Mild cognitive impairment (MCI) is the preclinical and transitional stage
between healthy ageing and dementia that may be a potential 'target'for interventions …

The pathology of Alzheimer disease (AD) damages structural and functional brain networks,
resulting in cognitive impairment. The results of recent connectomics studies have now …

The development of technologies to protect or enhance memory in older people is an
enduring goal of translational medicine. Here we describe repetitive (4-day) transcranial …

Background An increase in lifespan in our society is a double-edged sword that entails a
growing number of patients with neurocognitive disorders, Alzheimer's disease being the …

Accumulating evidence demonstrates that metabolic changes in the brain associated with
neuroinflammation, oxidative stress, and mitochondrial dysfunction play an important role in …

Introduction Neuronal-derived exosomal Aβ42, T-tau, and P-T181-tau have been
demonstrated to be biomarkers of Alzheimer's disease (AD). However, no study has …

Introduction. Screening tests play a crucial role in dementia diagnostics, thus they should be
very sensitive for mild cognitive impairment (MCI) assessment. Nowadays, the Mini-Mental …

Combined cognitive and physical exercise interventions have potential to elicit cognitive
benefits in older adults with mild cognitive impairment (MCI) or dementia. This meta-analysis …

This article reviews the cognitive changes that occur with normal aging, the structural and
functional correlates of these cognitive changes, and the prevalence and cognitive effects of …

Neuroimaging-based single subject prediction of brain disorders has gained increasing
attention in recent years. Using a variety of neuroimaging modalities such as structural …