Rheumatoid arthritis (RA) is a systemic auto-immune disease principally effecting synovial
joints. RA is characterized by immune cell infiltration in the joint. The presence of …

Rheumatoid arthritis (RA) is considered a chronic systemic, multi-factorial, inflammatory, and
progressive autoimmune disease affecting many people worldwide. While patients show …

Rheumatoid arthritis (RA) is the most common systemic inflammatory rheumatic disease. It is
associated with significant burden at the patient and societal level. Extensive efforts have …

Rheumatoid arthritis (RA) is a chronic autoimmune disease considered as a multistep
process spanning from the interaction of genetic (eg, shared epitope or non-HLA loci) …

Rheumatoid arthritis (RA) is a chronic systemic inflammatory disease mainly involving
synovial inflammation and articular bone destruction. RA is a heterogeneous disease with …

The presence of autoantibodies is one of the hallmarks of rheumatoid arthritis (RA). In the
past few decades, rheumatoid factors (autoantibodies that recognize the Fc-tail of …

Objective The presence of anti-citrullinated protein antibodies (ACPA) and IgM-rheumatoid
factor (IgM-RF) years before the clinical diagnosis of rheumatoid arthritis (RA) suggests they …

Measurement of two groups of autoantibodies, rheumatoid factor (RF) and anti-citrullinated
protein/peptide antibodies (ACPA) have gained increasing significance in the diagnosis and …

Rheumatoid arthritis (RA) is a chronic inflammatory syndrome with a strong autoimmune
component. The autoantigens in RA are neither tissue nor organ‐specific, but comprise a …

The etiology of autoimmune diseases is due to a combination of genetic predisposition and
environmental factors that alter the expression of immune regulatory genes through various …