• The specific situation of the patient. Unless otherwise provided for by national regulations,
off-label use of medication should be limited to situations where it is in the patient's interest …

Dilated cardiomyopathy (DCM) is a complex disease with multiple causes and various
pathogenic mechanisms. Despite improvements in the prognosis of patients with DCM in the …

Abstract Background and Aims Pathogenic desmoplakin (DSP) gene variants are
associated with the development of a distinct form of arrhythmogenic cardiomyopathy known …

Background: A novel risk calculator based on clinical characteristics and noninvasive tests
that predicts the onset of clinical sustained ventricular arrhythmias (VA) in patients with …

Background Desmin (DES) pathogenic variants cause a small proportion of arrhythmogenic
cardiomyopathy (ACM). Outcomes data on DES-related ACM are scarce. Objectives This …

BACKGROUND: Pathogenic variants in PKP2 (plakophilin-2) cause arrhythmogenic right
ventricular cardiomyopathy, a disease characterized by life-threatening arrhythmias and …

Aims This study aimed to explore the incidence of severe cardiac events in paediatric
arrhythmogenic right ventricular cardiomyopathy (ARVC) patients and ARVC penetrance in …

Background Electrocardiographic (ECG) findings in arrhythmogenic left ventricular
cardiomyopathy (ALVC) are limited to small case series. Objectives This study aimed to …

Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a heritable cardiomyopathy
characterized by a predominantly arrhythmic presentation. It represents the leading cause of …

Cardiomyopathies represent significant contributors to cardiovascular morbidity and
mortality. Over the past decades, a progress has occurred in characterization of the genetic …