Spinal cord injury: molecular mechanisms and therapeutic interventions

X Hu, W Xu, Y Ren, Z Wang, X He, R Huang… - Signal transduction and …, 2023 - nature.com
Spinal cord injury (SCI) remains a severe condition with an extremely high disability rate.
The challenges of SCI repair include its complex pathological mechanisms and the …

3D printed personalized nerve guide conduits for precision repair of peripheral nerve defects

K Liu, L Yan, R Li, Z Song, J Ding, B Liu… - Advanced …, 2022 - Wiley Online Library
The treatment of peripheral nerve defects has always been one of the most challenging
clinical practices in neurosurgery. Currently, nerve autograft is the preferred treatment …

[HTML][HTML] Functional nanomaterials in peripheral nerve regeneration: scaffold design, chemical principles and microenvironmental remodeling

Y Qian, H Lin, Z Yan, J Shi, C Fan - Materials Today, 2021 - Elsevier
Neuronal microenvironment imbalance is associated with successive and irreversible
pathophysiological changes and insufficient functional restoration after peripheral nerve …

Research trends in biomedical applications of two-dimensional nanomaterials over the last decade–a bibliometric analysis

S Zhu, Y Liu, Z Gu, Y Zhao - Advanced Drug Delivery Reviews, 2022 - Elsevier
Abstract Two-dimensional (2D) nanomaterials with versatile properties have been widely
applied in the field of biomedicine. Despite various studies having reviewed the …

Grooved fibers: Preparation principles through electrospinning and potential applications

L Zhan, J Deng, Q Ke, X Li, Y Ouyang, C Huang… - Advanced Fiber …, 2022 - Springer
The surface morphology of micro-and nano-scale fiber determines its application to a great
extent. At present, a variety of secondary morphology of microfibers and nanofibers, such as …

[HTML][HTML] Biomechanical microenvironment in peripheral nerve regeneration: from pathophysiological understanding to tissue engineering development

L Kong, X Gao, Y Qian, W Sun, Z You, C Fan - Theranostics, 2022 - ncbi.nlm.nih.gov
Peripheral nerve injury (PNI) caused by trauma, chronic disease and other factors may lead
to partial or complete loss of sensory, motor and autonomic functions, as well as neuropathic …

Biomimetic multilayer polycaprolactone/sodium alginate hydrogel scaffolds loaded with melatonin facilitate tendon regeneration

Z Yao, Y Qian, Y Jin, S Wang, J Li, WE Yuan… - Carbohydrate Polymers, 2022 - Elsevier
Tendon injury is one of the most common musculoskeletal diseases in the world, severely
challenging the public health care system. Electrospinning technique using polymer …

Bioactive 2D nanomaterials for neural repair and regeneration

X He, Y Zhu, B Ma, X Xu, R Huang, L Cheng… - Advanced Drug Delivery …, 2022 - Elsevier
Biomaterials have provided promising strategies towards improving the functions of injured
tissues of the nervous system. Recently, 2D nanomaterials, such as graphene, layered …

Bacterial cellulose-based composites for nerve tissue engineering

F Jabbari, V Babaeipour, S Bakhtiari - International Journal of Biological …, 2022 - Elsevier
Nerve injuries and neurodegenerative disorders are very serious and costly medical
challenges. Damaged nerve tissue may not be able to heal and regain its function, and scar …

Graphene-based material-mediated immunomodulation in tissue engineering and regeneration: mechanism and significance

L Ou, X Tan, S Qiao, J Wu, Y Su, W Xie, N Jin, J He… - ACS …, 2023 - ACS Publications
Tissue engineering and regenerative medicine hold promise for improving or even restoring
the function of damaged organs. Graphene-based materials (GBMs) have become a key …