The crucial roles of Bmi-1 in cancer: implications in pathogenesis, metastasis, drug resistance, and targeted therapies
J Xu, L Li, P Shi, H Cui, L Yang - International Journal of Molecular …, 2022 - mdpi.com
B-cell-specific Moloney murine leukemia virus integration region 1 (Bmi-1, also known as
RNF51 or PCGF4) is one of the important members of the PcG gene family, and is involved …
RNF51 or PCGF4) is one of the important members of the PcG gene family, and is involved …
Seminal plasma as a diagnostic fluid for male reproductive system disorders
Molecular biomarkers hold promise to advance the noninvasive diagnosis of male
reproductive system disorders and facilitate the identification and management of these …
reproductive system disorders and facilitate the identification and management of these …
Exosome-transmitted miR-128-3p increase chemosensitivity of oxaliplatin-resistant colorectal cancer
T Liu, X Zhang, L Du, Y Wang, X Liu, H Tian, L Wang… - Molecular cancer, 2019 - Springer
Background Oxaliplatin resistance is a major challenge for treatment of advanced colorectal
cancer (CRC). Both acquisition of epithelial-mesenchymal transition (EMT) and suppressed …
cancer (CRC). Both acquisition of epithelial-mesenchymal transition (EMT) and suppressed …
2, 4-dienoyl-CoA reductase regulates lipid homeostasis in treatment-resistant prostate cancer
Despite the clinical success of Androgen Receptor (AR)-targeted therapies, reactivation of
AR signalling remains the main driver of castration-resistant prostate cancer (CRPC) …
AR signalling remains the main driver of castration-resistant prostate cancer (CRPC) …
LncRNA PVT1 Facilitates Tumorigenesis and Progression of Glioma via Regulation of MiR-128-3p/GREM1 Axis and BMP Signaling Pathway
C Fu, D Li, X Zhang, N Liu, G Chi, X Jin - Neurotherapeutics, 2018 - Springer
The current research was aimed at probing into the role of long noncoding RNA (lncRNA)
PVT1 in the pathogenesis of glioma and the regulatory mechanism of PVT1/miR-128 …
PVT1 in the pathogenesis of glioma and the regulatory mechanism of PVT1/miR-128 …
Reduced miR-128 in breast tumor–initiating cells induces chemotherapeutic resistance via Bmi-1 and ABCC5
Y Zhu, F Yu, Y Jiao, J Feng, W Tang, H Yao… - Clinical Cancer …, 2011 - AACR
Purpose: Tumor-initiating cells are resistant to chemotherapy, but how microRNAs play a
role in regulating drug resistance of breast tumor–initiating cells (BT-IC) needs to be …
role in regulating drug resistance of breast tumor–initiating cells (BT-IC) needs to be …
Brain microRNAs and insights into biological functions and therapeutic potential of brain enriched miRNA-128
YK Adlakha, N Saini - Molecular cancer, 2014 - Springer
MicroRNAs, the non-coding single-stranded RNA of 19–25 nucleotides are emerging as
robust players of gene regulation. Plethora of evidences support that the ability of …
robust players of gene regulation. Plethora of evidences support that the ability of …
[HTML][HTML] microRNA-128 plays a critical role in human non-small cell lung cancer tumourigenesis, angiogenesis and lymphangiogenesis by directly targeting vascular …
J Hu, Y Cheng, Y Li, Z Jin, Y Pan, G Liu, S Fu… - European journal of …, 2014 - Elsevier
Recent studies have indicated that microRNAs (miRNAs) are important gene regulators that
play critical roles in biological processes and function as either tumour suppressors or …
play critical roles in biological processes and function as either tumour suppressors or …
The STEAP protein family: versatile oxidoreductases and targets for cancer immunotherapy with overlapping and distinct cellular functions
The human six‐transmembrane epithelial antigen of the prostate (STEAP) protein family
contains at least five homologous members. The necessity of multiple homologous STEAP …
contains at least five homologous members. The necessity of multiple homologous STEAP …
Metabolomic profiling reveals potential markers and bioprocesses altered in bladder cancer progression
Although alterations in xenobiotic metabolism are considered causal in the development of
bladder cancer, the precise mechanisms involved are poorly understood. In this study, we …
bladder cancer, the precise mechanisms involved are poorly understood. In this study, we …