Adiponectin: Structure, physiological functions, role in diseases, and effects of nutrition

K Khoramipour, K Chamari, AA Hekmatikar, A Ziyaiyan… - Nutrients, 2021 - mdpi.com
Adiponectin (a protein consisting of 244 amino acids and characterized by a molecular
weight of 28 kDa) is a cytokine that is secreted from adipose tissues (adipokine). Available …

Metabolic syndrome and hidradenitis suppurativa: Epidemiological, molecular, and therapeutic aspects

D Mintoff, F Benhadou, NP Pace… - International Journal of …, 2022 - Wiley Online Library
Hidradenitis suppurativa (HS) is a chronic, suppurative condition of the pilosebaceous unit.
Patients suffering from HS demonstrate a molecular profile in keeping with a state of …

Leptin and soluble leptin receptor in risk of colorectal cancer in the European Prospective Investigation into Cancer and Nutrition cohort

K Aleksandrova, H Boeing, M Jenab… - Cancer research, 2012 - AACR
Leptin, a peptide hormone produced primarily by the adipocytes, is hypothesized to play a
role in the pathogenesis of colorectal cancer (CRC). Soluble leptin receptor (sOB-R) may …

Influence of obesity and related metabolic alterations on colorectal cancer risk

K Aleksandrova, K Nimptsch, T Pischon - Current nutrition reports, 2013 - Springer
Obesity and related metabolic alterations have been implicated to play a role in colorectal
cancer risk. The metabolic syndrome, as assessed according to current international …

[PDF][PDF] Metformin increases hepatic leptin receptor and decreases steatosis in mice

X Tang, J Li, W Xiang, Y Cui, B Xie, X Wang, Z Xu… - J …, 2016 - researchgate.net
In addition to the ascertained efficacy as antidiabetic drug, metformin is increasingly being
used as weight-loss agent in obesity, and as insulin sensitizer in nonalcoholic fatty liver …

[HTML][HTML] Serum leptin concentration is associated with incident frailty in older adults

A Lana, A Valdés-Bécares, A Buño… - Aging and …, 2017 - ncbi.nlm.nih.gov
Obesity has been associated with higher risk of frailty in older adults, but the
pathophysiological mechanisms are unclear. No previous study has examined the …

[HTML][HTML] Lifestyle-induced decrease in fat mass improves adiponectin secretion in obese adults

KR Kelly, SD Navaneethan, TPJ Solomon… - Medicine and science …, 2014 - ncbi.nlm.nih.gov
Purpose Several studies have identified relationships between weight loss and adipokine
levels; however none have looked at the combined effect of aerobic exercise training with …

Can biomarkers be used to improve diagnosis and prediction of metabolic syndrome in childhood cancer survivors? A systematic review

VG Pluimakers, SS van Santen, M Fiocco… - Obesity …, 2021 - Wiley Online Library
Childhood cancer survivors (CCS) are at increased risk to develop metabolic syndrome
(MetS), diabetes, and cardiovascular disease. Common criteria underestimate adiposity and …

Adiposity, mediating biomarkers and risk of colon cancer in the European prospective investigation into cancer and nutrition study

K Aleksandrova, D Drogan, H Boeing… - … journal of cancer, 2014 - Wiley Online Library
Adiposity is a risk factor for colon cancer, but underlying mechanisms are not well
understood. We evaluated the extent to which 11 biomarkers with inflammatory and …

Adiponectin/leptin ratio and metabolic syndrome in a Mexican American population

S Mirza, HQ Qu, Q Li, PJ Martinez… - Clinical and …, 2011 - utpjournals.press
Objective Adiponectin and leptin play critical roles in the development of Metabolic
Syndrome (MetS). This study was designed to assess the feasibility of using circulating …