[HTML][HTML] Study of tree shrew biology and models: A booming and prosperous field for biomedical research

YG Yao, L Lu, RJ Ni, R Bi, C Chen… - Zoological …, 2024 - pmc.ncbi.nlm.nih.gov
The tree shrew (Tupaia belangeri) has long been proposed as a suitable alternative to non-
human primates (NHPs) in biomedical and laboratory research due to its close evolutionary …

[HTML][HTML] State of the Art in Sub-Phenotyping Midbrain Dopamine Neurons

V Basso, MD Döbrössy, LH Thompson, D Kirik… - Biology, 2024 - mdpi.com
Simple Summary This review delves into the differences between two important groups of
dopamine-producing brain cells, found in regions called the ventral tegmental area and the …

Increased MANF expression in the inferior temporal gyrus in patients with Alzheimer disease

XC Liu, XH Qi, H Fang, KQ Zhou, QS Wang… - Frontiers in Aging …, 2021 - frontiersin.org
Alzheimer disease (AD) is an aging-related disorder linked to endoplasmic reticulum (ER)
stress. The main pathologic feature of AD is the presence of extracellular senile plaques and …

Doublecortin-expressing neurons in Chinese tree shrew forebrain exhibit mixed rodent and primate-like topographic characteristics

JQ Ai, R Luo, T Tu, C Yang, J Jiang, B Zhang… - Frontiers in …, 2021 - frontiersin.org
Doublecortin (DCX) is transiently expressed in new-born neurons in the subventricular zone
(SVZ) and subgranular zone (SGZ) related to adult neurogenesis in the olfactory bulb (OB) …

Effect of senescence on the tyrosine hydroxylase and S100B immunoreactivity in the nigrostriatal pathway of the rat

GS Rocha, MAM Freire, KM Paiva, RF Oliveira… - Journal of Chemical …, 2022 - Elsevier
Senescence is a natural and progressive physiological event that leads to a series of
morphophysiological alterations in the organism. The brain is the most vulnerable organ to …

[HTML][HTML] Social avoidance behavior in male tree shrews and prosocial behavior in male mice toward unfamiliar conspecifics in the laboratory

RJ Ni, Y Tian, XY Dai, LS Zhao, JX Wei… - Zoological …, 2020 - ncbi.nlm.nih.gov
Adult male tree shrews vigorously defend against intruding male conspecifics. However, the
characteristics of social behavior have not been entirely explored in these males. In this …

Body surface area-based equivalent dose calculation in tree shrew

W Xia, ZJ Huang, YW Feng, AZ Tang… - Science progress, 2021 - journals.sagepub.com
Tree shrew (Tupaia belangeri) is a promising experimental animal in biomedical research,
but the equivalent doses of drugs between tree shrew and human and other animals has not …

WGCNA analysis of the subcutaneous fat transcriptome in a novel tree shrew model

Y Han, W Wang, J Jia, X Sun, D Kuang… - Experimental …, 2020 - journals.sagepub.com
Obesity involves genetic and environmental factors. The co-expression gene network in
relevant tissues in different obesity groups provides an entrance for profiling and identifying …

Comparative anatomical analysis of dopamine systems in Mus musculus and Peromyscus californicus

J Buck, MTC Manion, W Zhang, ER Glasper… - Brain Structure and …, 2022 - Springer
Dopamine plays important roles in motivational and social behaviors in mammals, and it has
been implicated in several human neurological and psychiatric disorders. Rodents are used …

实验室中雄性树鼩对陌生同类表现出社交回避行为而雄性小鼠则表现出亲社会行为

倪荣军, 田洋, 戴昕烨, 赵连生, 韦锦学, 周江宁… - 动物学研究, 2020 - zoores.ac.cn
成年雄性树鼩对入侵的同类防御剧烈. 但是, 这些雄性树鼩的社交行为特征尚未得到全面探究.
本研究中, 首先让雄性野生的中国树鼩和C57BL/6J 小鼠熟悉测试用的旷场箱子 …