Importance of selenium and selenoprotein for brain function: From antioxidant protection to neuronal signalling

ND Solovyev - Journal of inorganic biochemistry, 2015 - Elsevier
Multiple biological functions of selenium manifest themselves mainly via 25 selenoproteins
that have selenocysteine at their active centre. Selenium is vital for the brain and seems to …

Selenium nanoparticles for stress-resilient fish and livestock

B Sarkar, S Bhattacharjee, A Daware, P Tribedi… - Nanoscale research …, 2015 - Springer
The fisheries and livestock sectors capture the highest share of protein-rich animal food and
demonstrate accelerated growth as an agriculture subsidiary. Environmental pollution …

Features of the cytoprotective effect of selenium nanoparticles on primary cortical neurons and astrocytes during oxygen–glucose deprivation and reoxygenation

EA Turovsky, VN Mal'Tseva, RM Sarimov… - Scientific Reports, 2022 - nature.com
The study is aimed at elucidating the effect of selenium nanoparticles (SeNPs) on the death
of cells in the primary culture of mouse cerebral cortex during oxygen and glucose …

Modulation of Diabetes-Induced Oxidative Stress, Apoptosis, and Ca2+ Entry Through TRPM2 and TRPV1 Channels in Dorsal Root Ganglion and Hippocampus of …

MC Kahya, M Nazıroğlu, İS Övey - Molecular neurobiology, 2017 - Springer
Neuropathic pain and hippocampal injury can arise from the overload of diabetes-induced
calcium ion (Ca 2+) entry and oxidative stress. The transient receptor potential (TRP) …

Selenium and human health: witnessing a Copernican revolution?

E Jablonska, M Vinceti - … of Environmental Science and Health, Part …, 2015 - Taylor & Francis
In humans, selenium was hypothesized to lower the risk of several chronic diseases, mainly
due to the antioxidant activity of selenium-containing proteins. Recent epidemiologic and …

Synergic effects of doxorubicin and melatonin on apoptosis and mitochondrial oxidative stress in MCF-7 breast cancer cells: involvement of TRPV1 channels

PA Koşar, M Nazıroğlu, İS Övey, B Çiğ - The Journal of membrane biology, 2016 - Springer
Transient receptor transient receptor potential vanilloid 1 (TRPV1) is a Ca 2+-permeable
channel gated by oxidative stress and capsaicin (CAP) and modulated by melatonin (MEL) …

Cerium oxide nanoparticles protect endothelial cells from apoptosis induced by oxidative stress

S Chen, Y Hou, G Cheng, C Zhang, S Wang… - Biological trace element …, 2013 - Springer
Oxidative stress is well documented to cause injury to endothelial cells (ECs), which in turn
trigger cardiovascular diseases. Previous studies revealed that cerium oxide nanoparticles …

The neuroprotective action of dexmedetomidine on apoptosis, calcium entry and oxidative stress in cerebral ischemia-induced rats: Contribution of TRPM2 and …

H Akpınar, M Nazıroğlu, İS Övey, B Çiğ, O Akpınar - Scientific reports, 2016 - nature.com
Dexmedetomidine (DEX) may act as an antioxidant through regulation of TRPM2 and
TRPV1 channel activations in the neurons by reducing cerebral ischemia-induced oxidative …

Selenium mitigated aflatoxin B1-induced cardiotoxicity with potential regulation of 4 selenoproteins and ferroptosis signaling in chicks

L Zhao, Y Feng, ZJ Xu, NY Zhang, WP Zhang… - Food and Chemical …, 2021 - Elsevier
The aim of the present study was to explore the underlying mechanism of selenium (Se)-
mediated detoxification of aflatoxin B 1 (AFB 1)-induced cardiotoxicity in chicks. A Se …

Mitochondrial targeted cerium oxide nanoclusters for radiation protection and promoting hematopoiesis

L Yang, H Ran, Y Yin, J Liu, B Lu, X Ran… - International Journal …, 2024 - Taylor & Francis
Purpose Mitochondrial oxidative stress is an important factor in cell apoptosis. Cerium oxide
nanomaterials show great potential for scavenging free radicals and simulating superoxide …