The lung's unique extracellular matrix (ECM), while providing structural support for cells, is
critical in the regulation of developmental organogenesis, homeostasis and injury-repair …

The concerted interaction of genetic and environmental factors acts on the preterm human
immature lung with inflammation being the common denominator leading to the …

In contrast to early lung development, a process exemplified by the branching of the
developing airways, the later development of the immature lung remains very poorly …

Developing, regenerating, and repairing a lung all require interstitial resident fibroblasts
(iReFs) to direct the behavior of the epithelial stem cell niche. During lung development …

Bronchopulmonary dysplasia is a chronic lung disease associated with premature birth and
characterized by early lung injury. In this review we discuss some pitfalls, problems, and …

Alveolarization is the process by which the alveoli, the principal gas exchange units of the
lung, are formed. Along with the maturation of the pulmonary vasculature, alveolarization is …

Neonatal chronic lung disease, also known as bronchopulmonary dysplasia (BPD), is the
most common complication of premature birth, affecting up to 30% of very low birth weight …

Defective lung septation and angiogenesis, quintessential features of neonatal chronic lung
disease (CLD), typically result from lengthy exposure of developing lungs to mechanical …

Bronchopulmonary dysplasia (BPD) is a common complication of preterm birth that
contributes significantly to morbidity and mortality in neonatal intensive care units. BPD …

Exposure to hyperoxia, invasive mechanical ventilation, and systemic/local sepsis are
important antecedents of postnatal inflammation in the pathogenesis of bronchopulmonary …