A long-term complication of obesity is the development of type 2 diabetes (T2D). Patients
with T2D have been described as having epigenetic modifications. Epigenetics is the post …

The pathogenic mechanism of diabetic kidney disease (DKD) is involved in various
functions; however, its inadequate characterisation limits the availability of effective …

Diabetes is a metabolic disease characterized by hyperglycemia, which induces the
production of AGEs, ROS, inflammatory cytokines, and growth factors, leading to the …

Background. Long noncoding RNA (lncRNA) is involved in the occurrence and development
of diabetic kidney disease (DKD). It is necessary to identify the expression of lncRNA from …

Type 2 diabetes mellitus (T2DM) represents an important microvascular disease concerning
the kidney and the brain. Gut dysbiosis and microbiota-derived metabolites may be in …

Objective. Diabetic kidney disease (DKD) has been well recognized as a microvascular
complication of diabetes mellitus. Perfusion of intrarenal arteries is closely related with …

Long non-coding RNAs (lncRNAs) are RNAs with> 200 nucleotides that are unable to
encode proteins and are involved in gene expression regulation. LncRNAs have a key role …

Purpose: To determine the mechanism that long noncoding RNA NEAT1 (lncNEAT1)/miR-
320a competitive endogenous RNA (ceRNA) network regulates hypoxia-inducible factor–1α …

Objective: This study aimed to investigate the functions of lncRNA H19 on glomerular
endothelial structural damage of diabetic nephropathy (DN). Materials and Methods: Rats …

Mesangial cells (MCs), substantial cells for architecture and function of the glomerular tuft,
take a key role in progression of diabetic kidney disease (DKD). Despite long standing …