The treatment of multiple sclerosis (MS) has changed over the last 20 years. All
immunotherapeutic drugs target relapsing remitting MS (RRMS) and it still remains a …

Cognitive impairment is increasingly recognized to be a core feature of multiple sclerosis
(MS), with important implications for the everyday life of individuals with MS and for disease …

MRI studies have provided valuable insights into the structure and function of neural
networks, particularly in health and in classical neurodegenerative conditions such as …

Although multiple sclerosis has traditionally been considered a white matter disease,
extensive research documents the presence and importance of grey matter injury including …

Purpose To study deep gray matter susceptibility in multiple sclerosis (MS) by using
quantitative susceptibility mapping (QSM) and to assess the relationship between …

Abstract Neuroimaging using the 7-Tesla (7T) human magnetic resonance (MR) system is
rapidly gaining popularity after being approved for clinical use in the European Union and …

Fatigue is very common in multiple sclerosis (MS) and is often considered as its most
disabling symptom. Over the last 20 years, an increasing number of studies have evaluated …

Understanding the clinico-radiological paradox is important in the search for more sensitive
and specific surrogates of relapses and disability progression (such that they can be used to …

Background and Objectives Our aim was to investigate whether 18-kDa translocator protein
(TSPO) radioligand binding in gray matter (GM) predicts later disability progression in …

Background: In multiple sclerosis (MS), thalamic integrity is affected directly by
demyelination and neuronal loss, and indirectly by gray/white matter lesions outside the …