Novel diagnostic stewardship in infectious disease consists of interventions that modify
ordering, processing, and reporting of diagnostic tests to provide the right test for the right …

We provide an overview of diagnostic stewardship with key concepts that include the
diagnostic pathway and the multiple points where interventions can be implemented …

Blood cultures have been the staple of clinical microbiology laboratories for well over half a
century, but gaps remain in our ability to identify the causative agent in patients presenting …

The rapid and sensitive detection of pathogenic bacteria is highly demanded for early
warning of infectious disease epidemics and protection of human health. Herein, a reusable …

Abstract Background Bloodstream infections (BSIs) are a significant burden on the global
population and represent a key area of focus in the hospital environment. Blood culture (BC) …

Diagnostic stewardship decreases unnecessary antibiotic use in a way that is different from
and complementary to antibiotic stewardship. Further studies are needed to quantify the full …

Blood culture contamination (BCC) is the presence of specific commensal and
environmental organisms cultivated from a single blood culture set out of a blood culture …

Staphylococcus aureus (S. aureus) is a versatile and virulent pathogen and has become
one of the leading causes of life-threatening bloodstream infections, such as sepsis and …

Objectives: To evaluate the pattern of blood-culture utilization among a cohort of 6 hospitals
to identify potential opportunities for diagnostic stewardship. Methods: We completed a …

Objectives This study aimed to evaluate the clinical performance of plasma cell-free DNA
(cfDNA) next-generation sequencing (NGS) for pathogen detection in patients with sepsis …