Nanoparticles for targeted brain drug delivery: what do we know?

RGR Pinheiro, AJ Coutinho, M Pinheiro… - International Journal of …, 2021 - mdpi.com
The blood–brain barrier (BBB) is a barrier that separates the blood from the brain tissue and
possesses unique characteristics that make the delivery of drugs to the brain a great …

Surface functionalization and targeting strategies of liposomes in solid tumor therapy: A review

MK Riaz, MA Riaz, X Zhang, C Lin, KH Wong… - International journal of …, 2018 - mdpi.com
Surface functionalization of liposomes can play a key role in overcoming the current
limitations of nanocarriers to treat solid tumors, ie, biological barriers and physiological …

Comprehensive analysis of liposome formulation parameters and their influence on encapsulation, stability and drug release in glibenclamide liposomes

S Maritim, P Boulas, Y Lin - International journal of pharmaceutics, 2021 - Elsevier
An understanding of the factors that affect liposome size, drug loading, stability and drug
release is critical for the rational design of liposomes with desired pharmacokinetics and …

Brain penetrating peptides and peptide–drug conjugates to overcome the blood–brain barrier and target CNS diseases

X Zhou, QR Smith, X Liu - Wiley Interdisciplinary Reviews …, 2021 - Wiley Online Library
Nearly one in six people worldwide suffer from disorders of the central nervous system
(CNS). There is an urgent need for effective strategies to improve the success rates in CNS …

Recent advances on liposomal nanoparticles: synthesis, characterization and biomedical applications

Y Panahi, M Farshbaf… - Artificial cells …, 2017 - Taylor & Francis
Liposome is a new nanostructure for the encapsulation and delivery of bioactive agents.
There are a lot of bioactive materials that could be incorporated into liposomes including …

[HTML][HTML] Current update on nanoplatforms as therapeutic and diagnostic tools: A review for the materials used as nanotheranostics and imaging modalities

PI Siafaka, NÜ Okur, ID Karantas, ME Okur… - Asian Journal of …, 2021 - Elsevier
In the last decade, the use of nanotheranostics as emerging diagnostic and therapeutic tools
for various diseases, especially cancer, is held great attention. Up to date, several …

Chitosan-g-estrone Nanoparticles of Palbociclib Vanished Hypoxic Breast Tumor after Targeted Delivery: Development and Ultrasound/Photoacoustic Imaging

AK Mehata, V Singh, Vikas, N Singh… - … Applied Materials & …, 2023 - ACS Publications
Breast cancer is the leading cause of death among women globally. Approximately 80% of
all breast cancers diagnosed are overexpressed with estrogen receptors (ERs). In this study …

Liposomes for the treatment of brain cancer—A review

R Raju, WH Abuwatfa, WG Pitt, GA Husseini - Pharmaceuticals, 2023 - mdpi.com
Due to their biocompatibility, non-toxicity, and surface-conjugation capabilities, liposomes
are effective nanocarriers that can encapsulate chemotherapeutic drugs and facilitate …

[HTML][HTML] Astrocyte-derived exosomes protect hippocampal neurons after traumatic brain injury by suppressing mitochondrial oxidative stress and apoptosis

W Zhang, J Hong, H Zhang, W Zheng, Y Yang - Aging (Albany NY), 2021 - ncbi.nlm.nih.gov
In this study, we investigated the mechanisms through which astrocyte-derived exosomes
(AS-Exos) alleviate traumatic brain injury (TBI)-induced neuronal defects in TBI model rats …

Tumor microenvironment targeted nanotherapy

C Fernandes, D Suares, MC Yergeri - Frontiers in pharmacology, 2018 - frontiersin.org
Recent developments in nanotechnology have brought new approaches to cancer
diagnosis and therapy. While enhanced permeability and retention effect promotes nano …